| Literature DB >> 28385423 |
Una Ryan1, Andrea Paparini2, Charlotte Oskam2.
Abstract
Enteric parasites are major contributors to the global diarrhoeal disease load, infecting >67.2 million people. Their prevalence and clinical impact, however, are underestimated due to lack of adequate detection, which is largely still based on microscopy, particularly in developing countries. New commercially available enteric panel assays, which detect parasites (as well as bacteria and/or viruses) using multiplex PCR, offer enhanced sensitivity and specificity as well as the ability to detect mixed infections, and will play an important role in epidemiological surveillance and outbreak investigations. A major limitation of these technologies, however, particularly for developing countries, is the costs involved. Emerging technologies for low-resource, point-of-care (POC) settings have the potential to dramatically improve the cost and accuracy of enteric parasite detection in the future.Entities:
Keywords: Cryptosporidium; Cyclospora; Dientamoeba; Entamoeba; Giardia; emerging technologies; enteric panel assays
Mesh:
Year: 2017 PMID: 28385423 DOI: 10.1016/j.pt.2017.03.005
Source DB: PubMed Journal: Trends Parasitol ISSN: 1471-4922