Literature DB >> 28385363

"When information is not enough": A model for understanding BRCA-positive previvors' information needs regarding hereditary breast and ovarian cancer risk.

Marleah Dean1, Courtney L Scherr2, Meredith Clements3, Rachel Koruo3, Jennifer Martinez3, Amy Ross2.   

Abstract

OBJECTIVE: To investigate BRCA-positive, unaffected patients' - referred to as previvors - information needs after testing positive for a deleterious BRCA genetic mutation.
METHODS: 25 qualitative interviews were conducted with previvors. Data were analyzed using the constant comparison method of grounded theory.
RESULTS: Analysis revealed a theoretical model of previvors' information needs related to the stage of their health journey. Specifically, a four-stage model was developed based on the data: (1) pre-testing information needs, (2) post-testing information needs, (3) pre-management information needs, and (4) post-management information needs. Two recurring dimensions of desired knowledge also emerged within the stages-personal/social knowledge and medical knowledge.
CONCLUSIONS: While previvors may be genetically predisposed to develop cancer, they have not been diagnosed with cancer, and therefore have different information needs than cancer patients and cancer survivors. PRACTICE IMPLICATIONS: This model can serve as a framework for assisting healthcare providers in meeting the specific information needs of cancer previvors.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  BRCA; Decision-making; Genetics; Hereditary breast and ovarian cancer; Information; Previvors; Uncertainty

Mesh:

Year:  2017        PMID: 28385363     DOI: 10.1016/j.pec.2017.03.013

Source DB:  PubMed          Journal:  Patient Educ Couns        ISSN: 0738-3991


  15 in total

1.  "I Am Uncertain About What My Uncertainty Even Is": Men's Uncertainty and Information Management of Their BRCA-Related Cancer Risks.

Authors:  Emily A Rauscher; Marleah Dean; Gemme M Campbell-Salome
Journal:  J Genet Couns       Date:  2018-07-03       Impact factor: 2.537

2.  Anxiety and depression among racial/ethnic minorities and impoverished women testing positive for BRCA1/2 mutations in the United States.

Authors:  Kate E Dibble; Avonne E Connor
Journal:  Support Care Cancer       Date:  2022-03-26       Impact factor: 3.359

3.  An in-depth exploration of the post-test informational needs of BRCA1 and BRCA2 pathogenic variant carriers in Asia.

Authors:  Jeanette Yuen; Si Ming Fung; Chin Leong Sia; Mallika Venkatramani; Tarryn Shaw; Eliza Courtney; Shao-Tzu Li; Jianbang Chiang; Veronique Kiak-Mien Tan; Benita Kiat-Tee Tan; Joanne Ngeow
Journal:  Hered Cancer Clin Pract       Date:  2020-10-23       Impact factor: 2.857

4.  The needs of Southeast Asian BRCA mutation carriers considering risk-reducing salpingo-oophorectomy: a qualitative study.

Authors:  Hamizah Sa'at; Yew-Kong Lee; Sook-Yee Yoon; Siu Wan Wong; Yin Ling Woo; Kristine Barlow-Stewart; Nur Aishah Mohd Taib
Journal:  Fam Cancer       Date:  2021-02-19       Impact factor: 2.375

5.  Precision prophylaxis: Identifying the optimal timing for risk-reducing salpingo-oophorectomy based on type of BRCA1 and BRCA2 cluster region mutations.

Authors:  Ian Solsky; Jinbo Chen; Timothy R Rebbeck
Journal:  Gynecol Oncol       Date:  2020-01-07       Impact factor: 5.304

Review 6.  Patient experience of uncertainty in cancer genomics: a systematic review.

Authors:  Nicci Bartley; Christine Napier; Megan Best; Phyllis Butow
Journal:  Genet Med       Date:  2020-05-19       Impact factor: 8.822

7.  Ovarian Cancer Previvors: How to manage these patients?

Authors:  Jesus Paula Carvalho; Edmund Chada Baracat; Filomena Marino Carvalho
Journal:  Clinics (Sao Paulo)       Date:  2019-07-22       Impact factor: 2.365

8.  Engaging Men With BRCA-Related Cancer Risks: Practical Advice for BRCA Risk Management From Male Stakeholders.

Authors:  Marleah Dean; Gemme Campbell-Salome; Emily A Rauscher
Journal:  Am J Mens Health       Date:  2020 May-Jun

9.  Development of decision aids for female BRCA1 and BRCA2 mutation carriers in Germany to support preference-sensitive decision-making.

Authors:  Sibylle Kautz-Freimuth; Marcus Redaèlli; Kerstin Rhiem; Andrea Vodermaier; Lisa Krassuski; Kathrin Nicolai; Miriam Schnepper; Violetta Kuboth; Julia Dick; Vera Vennedey; Regina Wiedemann; Rita Schmutzler; Stephanie Stock
Journal:  BMC Med Inform Decis Mak       Date:  2021-06-05       Impact factor: 2.796

10.  Enhancing livestock vaccination decision-making through rapid diagnostic testing.

Authors:  Ashley F Railey; Felix Lankester; Tiziana Lembo; Richard Reeve; Gabriel Shirima; Thomas L Marsh
Journal:  World Dev Perspect       Date:  2019-12
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.