Literature DB >> 28384940

A Rare Case of Successfully Treated Coombs Negative Immune Haemolytic Anaemia in Pregnancy.

Pradip Kumar Saha1, Japleen Kaur2, Rashmi Bagga3, Jaswinder Kaur Kalra3, Arihant Jain4.   

Abstract

Immune haemolytic anaemia in pregnancy, although rare, but it can be life threatening. Severe anaemia with jaundice, unresponsive to blood transfusion can clinch the diagnosis of immune haemolytic anaemia. Our patient was a 27-year-old second gravida, with all the above features, but there was diagnostic challenge as her Coombs test was negative. A high index of suspicion and rapid response to glucocorticoids, pointed towards the diagnosis. Thereafter, the course of pregnancy and postpartum period was uneventful. Thus, successful maternal and fetal outcome can be achieved with prompt diagnosis and treatment.

Entities:  

Keywords:  Autoimmune; Direct coombs test; Haemolysis; Hyperbilirubinemia

Year:  2017        PMID: 28384940      PMCID: PMC5376850          DOI: 10.7860/JCDR/2017/22274.9409

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  8 in total

1.  A report of a rare case of autoimmune haemolytic anaemia in a patient with Hodgkin's disease in whom routine serology was negative.

Authors:  Archana Bajpayee; Anju Dubey; Anupam Verma; Rajendra K Chaudhary
Journal:  Blood Transfus       Date:  2013-05-08       Impact factor: 3.443

2.  IgA autoimmune haemolytic anaemia in a pregnant woman.

Authors:  Maria A Villa; Norma N Fantini; Nicoletta Revelli; Barbara Acaia; Cinzia Paccapelo; Maria C Manera; Maurizio Marconi
Journal:  Blood Transfus       Date:  2014-06-05       Impact factor: 3.443

Review 3.  Immune hemolytic anemia associated with negative routine serology.

Authors:  George Garratty
Journal:  Semin Hematol       Date:  2005-07       Impact factor: 3.851

Review 4.  How I treat autoimmune hemolytic anemias in adults.

Authors:  Klaus Lechner; Ulrich Jäger
Journal:  Blood       Date:  2010-06-14       Impact factor: 22.113

5.  Pregnancy Induced Autoimmune Warm Antibodies Hemolytic Anemia: A Case Report.

Authors:  D Laužikienė; D Ramašauskaitė; T Lūža; R Lenkutienė
Journal:  Geburtshilfe Frauenheilkd       Date:  2015-11       Impact factor: 2.915

6.  Erythrocyte autoantibodies, autoimmune haemolysis and pregnancy.

Authors:  R J Sokol; S Hewitt; B K Stamps
Journal:  Vox Sang       Date:  1982       Impact factor: 2.144

Review 7.  Rituximab in the treatment of autoimmune haematological disorders.

Authors:  Bernadette Garvey
Journal:  Br J Haematol       Date:  2008-03-03       Impact factor: 6.998

Review 8.  Autoimmune hemolytic anemia: From lab to bedside.

Authors:  R K Chaudhary; Sudipta Sekhar Das
Journal:  Asian J Transfus Sci       Date:  2014-01
  8 in total
  2 in total

1.  Autoimmune Hemolytic Anaemias in Pregnancy: Experience in a Tertiary Care Hospital in South India.

Authors:  Rao Preethi Venkatachala; C N Sheela; Seetharam Anandram; Cecil R Ross
Journal:  J Obstet Gynaecol India       Date:  2021-03-04

2.  Presumed immune-mediated haemolytic anaemia associated with pregnancy in a cat.

Authors:  Matthew A Kopke; Sarah Pemberton; Craig G Ruaux
Journal:  JFMS Open Rep       Date:  2019-04-04
  2 in total

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