Literature DB >> 28384938

Misoprostol Induced Convulsion-A Rare Side Effect of Misoprostol.

Nalini Sharma1, Rituparna Das2, Santa Singh Ahanthem3, Kalyani Reddy2.   

Abstract

Misoprostol, a synthetic prostaglandin E1 has wider application in obstetrics gynaecology. It has been recommended in the prophylaxis and treatment of Post Partum Haemorrhage (PPH) by Federation of Obstetrics and Gynaecology (FIGO), World Health Organisation (WHO) and American College of Obstetrics and Gynaecology (ACOG). It is a very safe drug associated with transient side-effects like fever, chills, nausea, vomiting, diarrhoea and abdominal pain. In the present case report patient had an unusual side effect of hyperpyrexia and convulsion after use of misoprostol for prophylaxis against PPH.

Entities:  

Keywords:  Hyperpyrexia; Postparum haemorrhage; Prostaglandin E1

Year:  2017        PMID： 28384938      PMCID： PMC5376767          DOI： 10.7860/JCDR/2017/23396.9189

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN： 0973-709X


  8 in total

Review 1.  Misoprostol and pregnancy.

Authors:  A B Goldberg; M B Greenberg; P D Darney
Journal:  N Engl J Med       Date:  2001-01-04       Impact factor: 91.245

2.  Severe hyperthermia following oral misoprostol in the immediate postpartum period.

Authors:  Y S Chong; S Chua; S Arulkumaran
Journal:  Obstet Gynecol       Date:  1997-10       Impact factor: 7.661

3.  ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists Number 76, October 2006: postpartum hemorrhage.

Authors: 
Journal:  Obstet Gynecol       Date:  2006-10       Impact factor: 7.661

4.  WHO multicentre randomised trial of misoprostol in the management of the third stage of labour.

Authors:  A M Gülmezoglu; J Villar; N T Ngoc; G Piaggio; G Carroli; L Adetoro; H Abdel-Aleem; L Cheng; G Hofmeyr; P Lumbiganon; C Unger; W Prendiville; A Pinol; D Elbourne; H El-Refaey; K Schulz
Journal:  Lancet       Date:  2001-09-01       Impact factor: 79.321

5.  Effects of misoprostol on pentylenetetrazol-induced seizures in mice.

Authors:  C Medeiros F das; M A Medeiros; V S Rao; E G Figueiredo
Journal:  Arq Neuropsiquiatr       Date:  1997-12       Impact factor: 1.420

6.  High fever following postpartum administration of sublingual misoprostol.

Authors:  J Durocher; J Bynum; W León; G Barrera; B Winikoff
Journal:  BJOG       Date:  2010-04-19       Impact factor: 6.531

7.  Delirium in an elderly woman possibly associated with administration of misoprostol.

Authors:  M R Morton; M E Robbins
Journal:  DICP       Date:  1991-02

8.  Misoprostol for termination of pregnancy-can it precipitate a seizure in a well controlled secondary epileptic tuberculoma patient?

Authors:  Pushparaj Mohanraj; Pradeep Kumar Garg; Deepa Maheswari Narasimalu
Journal:  J Turk Ger Gynecol Assoc       Date:  2010-03-01
  8 in total
  1 in total

1.  A rare case of misoprostol hypersensitivity.

Authors:  Rituparna Das; Subrat Panda; Nalini Sharma; Prakash Deb
Journal:  J Family Med Prim Care       Date:  2022-05-14
  1 in total

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