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Literature DB >> 28384135

Separase-securin complex: a cunning way to control chromosome segregation.

Martin R Singleton¹, Frank Uhlmann².

Abstract

Entities: Gene

Mesh：

Substances：
Securin
Separase

Year: 2017 PMID： 28384135 DOI： 10.1038/nsmb.3393

Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369

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26 in total

1. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

Authors: F Uhlmann; D Wernic; M A Poupart; E V Koonin; K Nasmyth
Journal: Cell Date: 2000-10-27 Impact factor: 41.582

2. The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene.

Authors: S Uzawa; I Samejima; T Hirano; K Tanaka; M Yanagida
Journal: Cell Date: 1990-09-07 Impact factor: 41.582

3. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis.

Authors: H Zou; T J McGarry; T Bernal; M W Kirschner
Journal: Science Date: 1999-07-16 Impact factor: 47.728

4. Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase.

Authors: I C Waizenegger; S Hauf; A Meinke; J M Peters
Journal: Cell Date: 2000-10-27 Impact factor: 41.582

5. The dual mechanism of separase regulation by securin.

Authors: Nadine C D Hornig; Philip P Knowles; Neil Q McDonald; Frank Uhlmann
Journal: Curr Biol Date: 2002-06-25 Impact factor: 10.834

6. Cut2 proteolysis required for sister-chromatid seperation in fission yeast.

Authors: H Funabiki; H Yamano; K Kumada; K Nagao; T Hunt; M Yanagida
Journal: Nature Date: 1996-05-30 Impact factor: 49.962

7. Regulation of human separase by securin binding and autocleavage.

Authors: Irene Waizenegger; Juan F Giménez-Abián; Dominik Wernic; Jan-Michael Peters
Journal: Curr Biol Date: 2002-08-20 Impact factor: 10.834

8. Resolution of chiasmata in oocytes requires separase-mediated proteolysis.

Authors: Nobuaki R Kudo; Katja Wassmann; Martin Anger; Melina Schuh; Karin G Wirth; Huiling Xu; Wolfgang Helmhart; Hiromi Kudo; Michael McKay; Bernard Maro; Jan Ellenberg; Peter de Boer; Kim Nasmyth
Journal: Cell Date: 2006-07-14 Impact factor: 41.582

Separase-securin complex: a cunning way to control chromosome segregation.

1. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

2. The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene.

3. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis.

4. Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase.

5. The dual mechanism of separase regulation by securin.

6. Cut2 proteolysis required for sister-chromatid seperation in fission yeast.

7. Regulation of human separase by securin binding and autocleavage.

8. Resolution of chiasmata in oocytes requires separase-mediated proteolysis.

9. Molecular mechanism for the regulation of yeast separase by securin.

10. Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.

Review 1. Ubiquitin signaling in cell cycle control and tumorigenesis.

Review 2. Ubiquitin-Proteasome System-Regulated Protein Degradation in Spermatogenesis.