Literature DB >> 28383580

A selective and light-up fluorescent probe for β-galactosidase activity detection and imaging in living cells based on an AIE tetraphenylethylene derivative.

Guoyu Jiang1, Guanjie Zeng, Wenping Zhu, Yongdong Li, Xiaobiao Dong, Guanxin Zhang, Xiaolin Fan, Jianguo Wang, Yongquan Wu, Ben Zhong Tang.   

Abstract

An aggregation induced emission (AIE) based bioimaging probe, TPE-Gal, was designed for light-up imaging of β-galactosidase in living cells. The applicability of TPE-Gal in imaging endogenous β-galactosidase activity was confirmed in OVCAR-3 cells.

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Year:  2017        PMID： 28383580     DOI： 10.1039/c7cc00249a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Reactive Species-Activatable AIEgens for Biomedical Applications.

Authors:  Xiaoying Kang; Yue Li; Shuai Yin; Wen Li; Ji Qi
Journal:  Biosensors (Basel)       Date:  2022-08-17

Review 2.  Enzyme-activatable fluorescent probes for β-galactosidase: from design to biological applications.

Authors:  Yongkang Yao; Yutao Zhang; Chenxu Yan; Wei-Hong Zhu; Zhiqian Guo
Journal:  Chem Sci       Date:  2021-07-16       Impact factor: 9.825

3.  In Situ Generated Novel 1H MRI Reporter for β-Galactosidase Activity Detection and Visualization in Living Tumor Cells.

Authors:  Shuo Gao; Lei Zhao; Zhiqiang Fan; Vikram D Kodibagkar; Li Liu; Hanqin Wang; Hong Xu; Mingli Tu; Bifu Hu; Chuanbin Cao; Zhenjian Zhang; Jian-Xin Yu
Journal:  Front Chem       Date:  2021-07-15       Impact factor: 5.221

4.  Rational Design for Multicolor Flavone-Based Fluorophores with Aggregation-Induced Emission Enhancement Characteristics and Applications in Mitochondria-Imaging.

Authors:  Liyan Liu; Yaohui Lei; Jianhui Zhang; Na Li; Fan Zhang; Huaqiao Wang; Feng He
Journal:  Molecules       Date:  2018-09-07       Impact factor: 4.411

5.  A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters.

Authors:  Lei Dong; Min-Yu Zhang; Hai-Hao Han; Yi Zang; Guo-Rong Chen; Jia Li; Xiao-Peng He; Sébastien Vidal
Journal:  Chem Sci       Date:  2021-12-07       Impact factor: 9.825
  5 in total

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