| Literature DB >> 28383264 |
Delong Mu1,2, Xinmou Wang1,2, Gong Chen1,2,3, Gang He1,2.
Abstract
An iridium-catalyzed ortho-C(sp2)-H amidation reaction of benzaldehydes with organic azides has been developed. A catalytic amount of 3,5-di(trifluoromethyl)aniline was used to promote the Ir-catalyzed directed C-H amination reaction through a transient aldimine intermediate. This reaction tolerates a broad scope of benzaldehyde substrates and works well with a range of aryl- and alkylsulfonyl azides.Entities:
Year: 2017 PMID： 28383264 DOI： 10.1021/acs.joc.7b00531
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354