Beth A Leeman-Markowski1,2, Steven C Schachter3. 1. NYU Comprehensive Epilepsy Center, Department of Neurology, New York University, 223 E. 34th St, New York, NY, 10016, USA. beth.leeman-markowski@nyumc.org. 2. VA New York Harbor Healthcare System-Manhattan Campus, Research Service, 423 E. 23rd St, New York, NY, 10010, USA. beth.leeman-markowski@nyumc.org. 3. Departments of Neurology, Beth Israel Deaconess Medical Center, Massachusetts General Hospital and Harvard Medical School, 125 Nashua St., Suite 324, Boston, MA, 02114, USA.
Abstract
PURPOSE OF REVIEW: Cognitive and behavioral treatments for epilepsy offer several advantages, as they are relatively low cost, are non-invasive, lack serious side effects, and facilitate patient participation. Their role in the management of epilepsy, however, is unclear. The following manuscript will critically review the efficacy data regarding psychological treatments for seizure reduction. RECENT FINDINGS: Encouraging results have been found for the cognitive behavioral therapy-based Reiter/Andrews approach and mindfulness or arousal-based programs (e.g., yoga, meditation, relaxation, and biofeedback). Most studies attained responder rates between 45 and 90%. Cognitive and behavioral interventions may be considered as low-risk adjuncts to standard therapies. Efficacy data are limited, however, by small numbers of subjects, inadequate randomization, controls, and blinding, brief trial durations, varying methodologies, and variability in the presentation of results. Additional clinical trials are warranted.
PURPOSE OF REVIEW: Cognitive and behavioral treatments for epilepsy offer several advantages, as they are relatively low cost, are non-invasive, lack serious side effects, and facilitate patient participation. Their role in the management of epilepsy, however, is unclear. The following manuscript will critically review the efficacy data regarding psychological treatments for seizure reduction. RECENT FINDINGS: Encouraging results have been found for the cognitive behavioral therapy-based Reiter/Andrews approach and mindfulness or arousal-based programs (e.g., yoga, meditation, relaxation, and biofeedback). Most studies attained responder rates between 45 and 90%. Cognitive and behavioral interventions may be considered as low-risk adjuncts to standard therapies. Efficacy data are limited, however, by small numbers of subjects, inadequate randomization, controls, and blinding, brief trial durations, varying methodologies, and variability in the presentation of results. Additional clinical trials are warranted.
Authors: Irena Balzekas; Vladimir Sladky; Petr Nejedly; Benjamin H Brinkmann; Daniel Crepeau; Filip Mivalt; Nicholas M Gregg; Tal Pal Attia; Victoria S Marks; Lydia Wheeler; Tori E Riccelli; Jeffrey P Staab; Brian Nils Lundstrom; Kai J Miller; Jamie Van Gompel; Vaclav Kremen; Paul E Croarkin; Gregory A Worrell Journal: Front Hum Neurosci Date: 2021-07-26 Impact factor: 3.473
Authors: Amy Shakeshaft; Naim Panjwani; Amber Collingwood; Holly Crudgington; Anna Hall; Danielle M Andrade; Christoph P Beier; Choong Yi Fong; Elena Gardella; Joanna Gesche; David A Greenberg; Khalid Hamandi; Jeanette Koht; Kheng Seang Lim; Rikke S Møller; Ching Ching Ng; Alessandro Orsini; Mark I Rees; Guido Rubboli; Kaja K Selmer; Pasquale Striano; Marte Syvertsen; Rhys H Thomas; Jana Zarubova; Mark P Richardson; Lisa J Strug; Deb K Pal Journal: Sci Rep Date: 2022-02-21 Impact factor: 4.379