Laser-induced photochemical synthesis of branched Ag@Au bimetallic nanodendrites as a prominent substrate for surface-enhanced Raman scattering spectroscopy.

The project of wielding laser light as a versatile tool for sculpting branched Ag@Au bimetallic nanocrystals with mean size of ~50 nm has been developed in this work. The moderate overgrowth of Ag species with negligible damage effect on the branched Ag@Au nanostructures was achieved by laser-induced photo-oxidation. The final Ag@Au nanodendrites exhibit superior surface enhanced Raman scattering (SERS) activities with an enhancement factor up to ~10¹¹ and a detection limit as low as ~10^-14 M. The pronounced feature should be attributed to the noticeable small-sized branches (<10 nm) and unique pronounced inter-metallic synergies. Our results have a promising potential for developing SERS-based ultrasensitive probes in biomedical application.