Parveen Athar1, Rodrigo Hasbun1, Melissa S Nolan2, Lucrecia Salazar1, Steven P Woods3, Kazim Sheikh1, Kristy O Murray2. 1. School of Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USA. 2. Department of Pediatrics, Section of Pediatric Tropical Medicine, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, One Baylor Plaza, BCM 320, Houston, Texas, 77030, USA. 3. Department of Psychology, University of Houston, Houston, Texas, USA.
Abstract
INTRODUCTION: Neuromuscular clinical manifestations during acute West Nile virus (WNV) infection are well documented; however, long-term neurologic outcomes still require investigation. METHODS: We conducted a long-term follow-up study in patients with history of WNV infection. Of the 117 patients who participated in neurologic and neurocognitive evaluations, 30 were referred for neuromuscular and electrodiagnostic evaluation based on abnormal findings. RESULTS: We found that 33% of these patients (10 of 30) showed abnormalities on nerve conduction and/or needle electromyography due to primary or secondary outcomes of WNV infection. Most common electrodiagnostic findings and causes of long-term disability were related to anterior horn cell poliomyelitis (WNV poliomyelitis). Electrical data on these patient populations were similar to those observed in chronic poliomyelitis. DISCUSSION: With more than 16,000 cases of WNV neuroinvasive disease reported across the USA since 1999, understanding clinical outcomes from infection will provide a resource for physicians managing long-term care of these patients. Muscle Nerve 57: 77-82, 2018.
INTRODUCTION: Neuromuscular clinical manifestations during acute West Nile virus (WNV) infection are well documented; however, long-term neurologic outcomes still require investigation. METHODS: We conducted a long-term follow-up study in patients with history of WNV infection. Of the 117 patients who participated in neurologic and neurocognitive evaluations, 30 were referred for neuromuscular and electrodiagnostic evaluation based on abnormal findings. RESULTS: We found that 33% of these patients (10 of 30) showed abnormalities on nerve conduction and/or needle electromyography due to primary or secondary outcomes of WNV infection. Most common electrodiagnostic findings and causes of long-term disability were related to anterior horn cell poliomyelitis (WNV poliomyelitis). Electrical data on these patient populations were similar to those observed in chronic poliomyelitis. DISCUSSION: With more than 16,000 cases of WNV neuroinvasive disease reported across the USA since 1999, understanding clinical outcomes from infection will provide a resource for physicians managing long-term care of these patients. Muscle Nerve 57: 77-82, 2018.
Authors: Marc Desforges; Alain Le Coupanec; Philippe Dubeau; Andréanne Bourgouin; Louise Lajoie; Mathieu Dubé; Pierre J Talbot Journal: Viruses Date: 2019-12-20 Impact factor: 5.048
Authors: Marija Santini; Sara Haberle; Snježana Židovec-Lepej; Vladimir Savić; Marija Kusulja; Neven Papić; Klaudija Višković; Ivana Župetić; Giovanni Savini; Ljubo Barbić; Irena Tabain; Marko Kutleša; Vladimir Krajinović; Tanja Potočnik-Hunjadi; Elizabeta Dvorski; Tamara Butigan; Gordana Kolaric-Sviben; Vladimir Stevanović; Lana Gorenec; Ivana Grgić; Filip Glavač; Armin Mehmedović; Eddy Listeš; Tatjana Vilibić-Čavlek Journal: Pathogens Date: 2022-01-02