| Literature DB >> 28380367 |
Joel F Habener1, Violeta Stanojevic2.
Abstract
The gut is believed to be the source of GLP-1 that augments insulin secretion in response to oral nutrients. In this issue of Cell Metabolism, Chambers et al. (2017) shift the paradigm by finding that GLP-1 produced within the islets of the pancreas, and not the gut, is responsible for the incretin effect in mice.Entities:
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Year: 2017 PMID： 28380367 DOI： 10.1016/j.cmet.2017.03.020
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287