Kristen M Beavers1, Daniel P Beavers2, Sarah B Martin1, Anthony P Marsh1, Mary F Lyles3, Leon Lenchik4, Sue A Shapses5, Barbara J Nicklas3. 1. Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina. 2. Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina. 3. Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Winston-Salem, North Carolina. 4. Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina. 5. Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey.
Abstract
BACKGROUND: To examine the effect of exercise modality during weight loss on hip and spine bone mineral density (BMD) in overweight and obese, older adults. METHODS: This analysis compared data from two 5-month, randomized controlled trials of caloric restriction (CR; inducing 5-10% weight loss) with either resistance training (RT) or aerobic training (AT) in overweight and obese, older adults. Participants in the RT + CR study underwent 3 days/week of 8 upper/lower body exercises (3 sets, 10 repetitions at 70% 1 RM) and participants in the AT+CR study underwent 4 days/week of treadmill walking (30 min at 65-70% heart rate reserve). BMD at the total hip, femoral neck, and lumbar spine was assessed via dual-energy X-ray absorptiometry at baseline and 5 months. RESULTS: A total of 123 adults (69.4 ± 3.5 years, 67% female, 81% Caucasian) participated in the RT+CR (n = 60) and AT+CR (n = 63) interventions. Average weight loss was 5.7% (95% CI: 4.6-6.7%) and 8.2% (95% CI: 7.2-9.3%) in RT+CR and AT+CR groups, respectively. After adjustment for age, gender, race, baseline BMI and BMD, and weight change, differential treatment effects were observed for total hip and femoral neck (both p < .05), but not lumbar spine. Total hip (1.83 [-3.90, 7.55] mg/cm2) and femoral neck (9.14 [-0.70, 18.98] mg/cm2) BMD was unchanged in RT+CR participants, and modestly decreased in AT+CR participants (total hip: -7.01 [-12.73, -1.29] mg/cm2; femoral neck: -5.36 [-14.92, 4.20] mg/cm2). CONCLUSIONS: Results suggest performing resistance, rather than aerobic, training during CR may attenuate loss of hip and femoral neck BMD in overweight and obese older adults. Findings warrant replication from a long-term, adequately powered, RCT.
BACKGROUND: To examine the effect of exercise modality during weight loss on hip and spine bone mineral density (BMD) in overweight and obese, older adults. METHODS: This analysis compared data from two 5-month, randomized controlled trials of caloric restriction (CR; inducing 5-10% weight loss) with either resistance training (RT) or aerobic training (AT) in overweight and obese, older adults. Participants in the RT + CR study underwent 3 days/week of 8 upper/lower body exercises (3 sets, 10 repetitions at 70% 1 RM) and participants in the AT+CR study underwent 4 days/week of treadmill walking (30 min at 65-70% heart rate reserve). BMD at the total hip, femoral neck, and lumbar spine was assessed via dual-energy X-ray absorptiometry at baseline and 5 months. RESULTS: A total of 123 adults (69.4 ± 3.5 years, 67% female, 81% Caucasian) participated in the RT+CR (n = 60) and AT+CR (n = 63) interventions. Average weight loss was 5.7% (95% CI: 4.6-6.7%) and 8.2% (95% CI: 7.2-9.3%) in RT+CR and AT+CR groups, respectively. After adjustment for age, gender, race, baseline BMI and BMD, and weight change, differential treatment effects were observed for total hip and femoral neck (both p < .05), but not lumbar spine. Total hip (1.83 [-3.90, 7.55] mg/cm2) and femoral neck (9.14 [-0.70, 18.98] mg/cm2) BMD was unchanged in RT+CR participants, and modestly decreased in AT+CR participants (total hip: -7.01 [-12.73, -1.29] mg/cm2; femoral neck: -5.36 [-14.92, 4.20] mg/cm2). CONCLUSIONS: Results suggest performing resistance, rather than aerobic, training during CR may attenuate loss of hip and femoral neck BMD in overweight and obese older adults. Findings warrant replication from a long-term, adequately powered, RCT.
Authors: Krupa Shah; Reina Armamento-Villareal; Nehu Parimi; Suresh Chode; David R Sinacore; Tiffany N Hilton; Nicola Napoli; Clifford Qualls; Dennis T Villareal Journal: J Bone Miner Res Date: 2011-12 Impact factor: 6.741
Authors: Dennis T Villareal; Krupa Shah; Marian R Banks; David R Sinacore; Samuel Klein Journal: J Clin Endocrinol Metab Date: 2008-03-25 Impact factor: 5.958
Authors: Jason Fanning; Michael P Walkup; Walter T Ambrosius; Lawrence R Brawley; Edward H Ip; Anthony P Marsh; W Jack Rejeski Journal: J Behav Med Date: 2017-11-22
Authors: Kristen M Beavers; Michael P Walkup; Ashley A Weaver; Leon Lenchik; Stephen B Kritchevsky; Barbara J Nicklas; Walter T Ambrosius; Joel D Stitzel; Thomas C Register; Sue A Shapses; Anthony P Marsh; W Jack Rejeski Journal: J Bone Miner Res Date: 2018-08-07 Impact factor: 6.741
Authors: Mary L Greaney; Steven A Cohen; Christie L Ward-Ritacco; Deborah Riebe Journal: Int J Environ Res Public Health Date: 2019-03-16 Impact factor: 3.390
Authors: Myong-Won Seo; Sung-Woo Jung; Sung-Woo Kim; Jung-Min Lee; Hyun Chul Jung; Jong-Kook Song Journal: Int J Environ Res Public Health Date: 2021-06-23 Impact factor: 3.390