Literature DB >> 28378607

New Capabilities of EvoBot: A Modular, Open-Source Liquid-Handling Robot.

Farzad Nejatimoharrami1, Andres Faina1, Kasper Stoy1.   

Abstract

We introduce a robot developed to perform feedback-based experiments, such as droplet experiments, a common type of experiments in artificial chemical life research. These experiments are particularly well suited for automation because they often stretch over long periods of time, possibly hours, and often require that the human takes action in response to observed events such as changes in droplet size, count, shape, or clustering or declustering of multiple droplets. Our robot is designed to monitor long-term experiments and, based on the feedback from the experiment, interact with it. The combination of precise automation, accurately collected experiment data, and integrated analysis and modeling software makes real-time interaction with the experiment feasible, as opposed to traditional offline processing of experiments. Last but not least, we believe the low cost of our platform can promote artificial life research. Furthermore, prevalently, findings from an experiment will inspire redesign for novel experiments. In addition, the robot's open-source software enables easy modification of experiments. We will cover two case studies for application of our robot in feedback-based experiments and demonstrate how our robot can not only automate these experiments, collect data, and interact with the experiments intelligently but also enable chemists to perform formerly infeasible experiments.

Entities:  

Keywords:  Robotics and instrumentation; automated biology; informatics and software; programming; systems engineering

Mesh:

Substances:

Year:  2017        PMID: 28378607     DOI: 10.1177/2472630316689285

Source DB:  PubMed          Journal:  SLAS Technol        ISSN: 2472-6303            Impact factor:   3.047


  4 in total

1.  Mostly 3D printed chemical synthesis robot.

Authors:  Dhanalakshmi Vadivel; Diego Savio Branciforti; Othman Kerroumi; Marco Dondi; Daniele Dondi
Journal:  HardwareX       Date:  2022-04-22

2.  Exploiting open source 3D printer architecture for laboratory robotics to automate high-throughput time-lapse imaging for analytical microbiology.

Authors:  Sarah H Needs; Tai The Diep; Stephanie P Bull; Anton Lindley-Decaire; Partha Ray; Alexander D Edwards
Journal:  PLoS One       Date:  2019-11-19       Impact factor: 3.240

3.  OpenWorkstation: A modular open-source technology for automated in vitro workflows.

Authors:  Sebastian Eggert; Pawel Mieszczanek; Christoph Meinert; Dietmar W Hutmacher
Journal:  HardwareX       Date:  2020-10-20

Review 4.  Unlocking the efficiency of genomics laboratories with robotic liquid-handling.

Authors:  Houriiyah Tegally; James Emmanuel San; Jennifer Giandhari; Tulio de Oliveira
Journal:  BMC Genomics       Date:  2020-10-20       Impact factor: 3.969

  4 in total

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