OBJECTIVE: Effective treatments for rheumatoid arthritis (RA) fatigue are limited. We tested the effect of a pedometer-based intervention on increasing physical activity and decreasing fatigue among individuals with RA. METHODS: Participants completed baseline questionnaires; had 1 week of activity monitoring; were randomized to control (education [EDUC]), pedometer and step-monitoring diary (PED), or pedometer and diary plus step targets (PED+) groups, and were followed for 21 weeks. At week 10, questionnaires were administered by phone to all participants. During the final week, all participants again had 1 week of activity monitoring. Primary outcomes were changes in average weekly steps and fatigue (Patient-Reported Outcomes Measurement Information System 7-item questionnaire) from baseline to week 21. Secondary outcomes were self-reported disease activity, physical function, pain interference, and depressive symptoms. Changes in steps were tested using a linear mixed model. Changes in fatigue were tested with repeated-measures models, including baseline, week-10, and week-21 scores. RESULTS: A total of 96 individuals participated. Eight did not complete the 21-week assessments. Both intervention groups significantly increased steps (+1,441 [P = 0.004] for PED and +1,656 [P = 0.001] for PED+), and the EDUC group decreased steps (-747 [P = 0.14]) (group-by-time interaction P = 0.0025). Between-group changes in fatigue were not significantly different (interaction P = 0.21). Mean changes in fatigue scores from baseline to week 21 were -1.6 (with-group P = 0.26), -3.2 (P = 0.02), and -4.8 (P = 0.0002) for EDUC, PED, and PED+ groups, respectively. Function and self-reported disease activity also improved in the PED and PED+ groups. CONCLUSION: Provision of pedometers, with and without providing step targets, was successful in increasing activity levels and decreasing fatigue in this sample of individuals with RA.
RCT Entities:
OBJECTIVE: Effective treatments for rheumatoid arthritis (RA) fatigue are limited. We tested the effect of a pedometer-based intervention on increasing physical activity and decreasing fatigue among individuals with RA. METHODS:Participants completed baseline questionnaires; had 1 week of activity monitoring; were randomized to control (education [EDUC]), pedometer and step-monitoring diary (PED), or pedometer and diary plus step targets (PED+) groups, and were followed for 21 weeks. At week 10, questionnaires were administered by phone to all participants. During the final week, all participants again had 1 week of activity monitoring. Primary outcomes were changes in average weekly steps and fatigue (Patient-Reported Outcomes Measurement Information System 7-item questionnaire) from baseline to week 21. Secondary outcomes were self-reported disease activity, physical function, pain interference, and depressive symptoms. Changes in steps were tested using a linear mixed model. Changes in fatigue were tested with repeated-measures models, including baseline, week-10, and week-21 scores. RESULTS: A total of 96 individuals participated. Eight did not complete the 21-week assessments. Both intervention groups significantly increased steps (+1,441 [P = 0.004] for PED and +1,656 [P = 0.001] for PED+), and the EDUC group decreased steps (-747 [P = 0.14]) (group-by-time interaction P = 0.0025). Between-group changes in fatigue were not significantly different (interaction P = 0.21). Mean changes in fatigue scores from baseline to week 21 were -1.6 (with-group P = 0.26), -3.2 (P = 0.02), and -4.8 (P = 0.0002) for EDUC, PED, and PED+ groups, respectively. Function and self-reported disease activity also improved in the PED and PED+ groups. CONCLUSION: Provision of pedometers, with and without providing step targets, was successful in increasing activity levels and decreasing fatigue in this sample of individuals with RA.
Authors: Graeme Mattison; Oliver Canfell; Doug Forrester; Chelsea Dobbins; Daniel Smith; Juha Töyräs; Clair Sullivan Journal: J Med Internet Res Date: 2022-07-01 Impact factor: 7.076
Authors: Beatriz Y Hanaoka; Matthew P Ithurburn; Cody A Rigsbee; S Louis Bridges; Douglas R Moellering; Barbara Gower; Marcas Bamman Journal: Arthritis Care Res (Hoboken) Date: 2019-01-04 Impact factor: 4.794
Authors: Andres Reinoso-Cobo; Pekka Anttila; Ana Belen Ortega-Avila; Pablo Cervera-Garvi; Eva Lopezosa-Reca; Ana Marchena-Rodriguez; Laura Ramos-Petersen; Gabriel Gijon-Nogueron Journal: Int J Med Sci Date: 2021-03-30 Impact factor: 3.738
Authors: H O Fawole; D T Felson; L A Frey-Law; S R Jafarzadeh; A Dell'Isola; M P Steultjens; M C Nevitt; C E Lewis; J L Riskowski; Sfm Chastin Journal: Scand J Rheumatol Date: 2021-03-20 Impact factor: 3.057
Authors: Robin P Silverstein; Melissa VanderVos; Heather Welch; Alex Long; Charlotte D Kaboré; Jennifer M Hootman Journal: MMWR Morb Mortal Wkly Rep Date: 2018-11-23 Impact factor: 17.586
Authors: Sally A M Fenton; Joan L Duda; Jet J C S Veldhuijzen van Zanten; George S Metsios; George D Kitas Journal: Mediterr J Rheumatol Date: 2020-03-31