| Literature DB >> 28378048 |
P Eberwein1, T Reinhard2.
Abstract
Reconstruction of the limbal stem cell niche in patients with limbal stem cell insufficiency remains one of the most challenging tasks in the treatment of ocular surface diseases. Ex vivo expansion of limbal stem cells still has potential for optimization despite positive reports in centers worldwide. New biomaterials as well as alternative cell sources for the reconstruction of the limbal stem cell niche have been published in recent years. The aim of this review is to provide insight into new biomaterials and cell sources which may find their way into clinical routine in the upcoming decades.Entities:
Keywords: Complications; Limbal stem cell insufficiency; Ocular surface; Safety; Tissue engineering
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Year: 2017 PMID: 28378048 DOI: 10.1007/s00347-017-0463-5
Source DB: PubMed Journal: Ophthalmologe ISSN: 0941-293X Impact factor: 1.059