| Literature DB >> 28375452 |
Laurie S Davis1, Andreas M Reimold1,2.
Abstract
This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science are predicted to enable accelerated progress towards improved SLE diagnosis and personalized approaches to treatment.Entities:
Keywords: B cells; biological therapies; clinical trials and methods; immunotherapy; systemic lupus erythematosus and autoimmunity
Mesh:
Substances:
Year: 2017 PMID: 28375452 PMCID: PMC5850311 DOI: 10.1093/rheumatology/kew417
Source DB: PubMed Journal: Rheumatology (Oxford) ISSN: 1462-0324 Impact factor: 7.580