| Literature DB >> 28373495 |
Shaun Goodyear, Ralph Brinster.
Abstract
Spermatogonial stem cells (SSCs) are located in the basal region of the seminiferous tubules and provide a self-renewing reservoir from which progenitor spermatogonia arise and transiently amplify in number before transition to a differentiating state. SSC transplantation involves grafting mouse testicular cells into the seminiferous tubules of an aspermic recipient testis that is generated either by chemical (e.g., busulfan) treatment or genetic mutations.Entities:
Mesh:
Year: 2017 PMID: 28373495 DOI: 10.1101/pdb.prot094235
Source DB: PubMed Journal: Cold Spring Harb Protoc ISSN: 1559-6095