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Literature DB >> 28372715

Management of Hyperglycemic Crises: Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State.

Maya Fayfman¹, Francisco J Pasquel¹, Guillermo E Umpierrez².

Abstract

Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are the most serious and life-threatening hyperglycemic emergencies in diabetes. DKA is more common in young people with type 1 diabetes and HHS in adult and elderly patients with type 2 diabetes. Features of the 2 disorders with ketoacidosis and hyperosmolality may coexist. Both are characterized by insulinopenia and severe hyperglycemia. Early diagnosis and management are paramount. Treatment is aggressive rehydration, insulin therapy, electrolyte replacement, and treatment of underlying precipitating events. This article reviews the epidemiology, pathogenesis, diagnosis, and management of hyperglycemic emergencies.

Entities: Chemical Disease Gene Species

Keywords: Diabetes; Diabetic ketoacidosis; Hyperglycemic emergencies; Hyperglycemic hyperosmolar state; Management of hyperglycemic emergencies

Mesh：

Substances：

Year: 2017 PMID： 28372715 PMCID： PMC6535398 DOI： 10.1016/j.mcna.2016.12.011

Source DB: PubMed Journal: Med Clin North Am ISSN： 0025-7125 Impact factor: 5.456

115 in total

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36 in total

1. Clinical Outcomes in Patients With Isolated or Combined Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State: A Retrospective, Hospital-Based Cohort Study.

Authors: Francisco J Pasquel; Katerina Tsegka; Heqiong Wang; Saumeth Cardona; Rodolfo J Galindo; Maya Fayfman; Georgia Davis; Priyathama Vellanki; Alexandra Migdal; Unjali Gujral; K M Venkat Narayan; Guillermo E Umpierrez
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Journal: Int J Mol Sci Date: 2022-06-16 Impact factor: 6.208

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Journal: Medicine (Baltimore) Date: 2021-05-28 Impact factor: 1.817