Literature DB >> 28372302

Advance of DNA and CCPs-based nanocarriers in drug delivery systems.

Yu Wu1, Xihui Yao1, Yun Chen1, Yinping Li2, Weiqun Tian1.   

Abstract

Development of smart and functional polymeric carriers, which enable controlled or timed release of a bioactive material, thereby providing a better dosing pattern and minimizing side effects, becomes a new requirement in the field of drug delivery. In the recent few decades, a great many advancements of polymer synthetic methods have led to a new generation of bioactive polymers' applications as drug controlled release carriers. In this review, we focus on the use of bioactive polymers for drug delivery system, with a particular in the utility of DNA-based nanocarriers and cell-penetrating peptides (CCPs)-based nanocarriers to provide precision control for drug targeting or stimuli responsive systems.

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Keywords:  DNA; cell-penetrating peptides; drug delivery systems; nanocarriers; targeting

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Year:  2017        PMID: 28372302     DOI: 10.3233/BME-171648

Source DB:  PubMed          Journal:  Biomed Mater Eng        ISSN: 0959-2989            Impact factor:   1.300


  1 in total

1.  Three-dimensional DNA tweezers serve as modular DNA intelligent machines for detection and regulation of intracellular microRNA.

Authors:  Lin Zhou; Mingxuan Gao; Weiling Fu; Yunxia Wang; Dan Luo; Kai Chang; Ming Chen
Journal:  Sci Adv       Date:  2020-05-29       Impact factor: 14.136

  1 in total

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