Literature DB >> 28371579

A One-Pot Multicomponent 1,3-Dipolar Cycloaddition Strategy: Combinatorial Synthesis of Dihydrothiophenone-Engrafted Dispiro Hybrid Heterocycles.

Mani Anusha Rani1, Sundaravel Vivek Kumar1, Karuppiah Malathi1, Muthumani Muthu1, Abdulrahman I Almansour2, Raju Suresh Kumar2, Raju Ranjith Kumar1.   

Abstract

The combinatorial syntheses of a library of novel dihydrothiophenone-engrafted dispiro oxindole/indenoquinoxaline-pyrrolidine/pyrrolothiazole/indolizine hybrid heterocycles have been realized through a chemo-, regio-, and stereoselective multicomponent 1,3-dipolar cycloaddition strategy.

Entities:  

Keywords:  1,3-dipolar cycloaddition; azomethine ylide; dihydrothiophen-3(2H)-ones; dispiro heterocycles; multicomponent reaction

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Substances：

Year:  2017        PMID： 28371579     DOI： 10.1021/acscombsci.6b00186

Source DB:  PubMed          Journal:  ACS Comb Sci        ISSN： 2156-8944            Impact factor:   3.784


  2 in total

1.  Three-Component Access to Functionalized Spiropyrrolidine Heterocyclic Scaffolds and Their Cholinesterase Inhibitory Activity.

Authors:  Sarra Boudriga; Saoussen Haddad; Vikneswaran Murugaiyah; Moheddine Askri; Michael Knorr; Carsten Strohmann; Christopher Golz
Journal:  Molecules       Date:  2020-04-23       Impact factor: 4.411

Review 2.  Recent applications of ninhydrin in multicomponent reactions.

Authors:  Suven Das
Journal:  RSC Adv       Date:  2020-05-18       Impact factor: 4.036
  2 in total

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