Giuseppe Angelelli1, Marco Moschetta2, Luisa Limongelli3, Annamaria Albergo1, Emanuela Lacalendola1, Francesco Brindicci3, Gianfranco Favia3, Eugenio Maiorano2. 1. DIM, Interdisciplinary Department of Medicine, Section of Diagnostic Imaging, Aldo Moro University of Bari Medical School, Bari, Italy. 2. DETO, Department of Emergency and Organ Transplantations, Section of Pathological Anatomy, University of Bari Medical School, Bari, Italy. 3. DIM, Interdisciplinary Department of Medicine, Section of Odontostomatology and Surgery, Aldo Moro University of Bari Medical School, Bari, Italy.
Abstract
BACKGROUND: Preoperative staging is crucial for oral cancer management. The purpose of this study was to assess the tumor thickness using ultrasound and to correlate the level of histological infiltration with the tumor superficial extension and lesion thickness. METHODS: Thirty-two subjects affected by oral cavity carcinoma were prospectively evaluated with intraoral ultrasound. The ultrasound sensitivity, the correlation between the ultrasound level of infiltration, and lesion diameters and thickness were assessed. RESULTS: A 91% ultrasound sensitivity was found with no significant correlation between tumor diameter and level of histological infiltration (P >.05). A thickness of <2 mm was associated to tumor extension to the lamina propria, a value of >6 mm to muscular layer infiltration. Lymph adenopathies were identified in 21% of cases, associated to muscular layer infiltration in all cases. CONCLUSION: In the study of early oral cavity tumors, ultrasound is accurate for demonstrating the level of tumor infiltration and contributes to the therapeutic choice.
BACKGROUND: Preoperative staging is crucial for oral cancer management. The purpose of this study was to assess the tumor thickness using ultrasound and to correlate the level of histological infiltration with the tumor superficial extension and lesion thickness. METHODS: Thirty-two subjects affected by oral cavity carcinoma were prospectively evaluated with intraoral ultrasound. The ultrasound sensitivity, the correlation between the ultrasound level of infiltration, and lesion diameters and thickness were assessed. RESULTS: A 91% ultrasound sensitivity was found with no significant correlation between tumor diameter and level of histological infiltration (P >.05). A thickness of <2 mm was associated to tumor extension to the lamina propria, a value of >6 mm to muscular layer infiltration. Lymph adenopathies were identified in 21% of cases, associated to muscular layer infiltration in all cases. CONCLUSION: In the study of early oral cavity tumors, ultrasound is accurate for demonstrating the level of tumor infiltration and contributes to the therapeutic choice.
Authors: Dario Di Stasio; Marco Montella; Antonio Romano; Giuseppe Colella; Rosario Serpico; Alberta Lucchese Journal: Cancers (Basel) Date: 2022-01-23 Impact factor: 6.639