Literature DB >> 28370403

NPM1 mutation but not RUNX1 mutation or multilineage dysplasia defines a prognostic subgroup within de novo acute myeloid leukemia lacking recurrent cytogenetic abnormalities in the revised 2016 WHO classification.

Olga K Weinberg1, Christopher J Gibson2, Traci M Blonquist3, Donna Neuberg3, Olga Pozdnyakova4, Frank Kuo4, Benjamin L Ebert2, Robert P Hasserjian5.   

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Year:  2017        PMID： 28370403      PMCID： PMC5470583          DOI： 10.1002/ajh.24739

Source DB:  PubMed          Journal:  Am J Hematol        ISSN： 0361-8609            Impact factor:   10.047


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  6 in total

1.  The prognostic value of multilineage dysplasia in de novo acute myeloid leukemia patients with intermediate-risk cytogenetics is dependent on NPM1 mutational status.

Authors:  Marina Díaz-Beyá; María Rozman; Marta Pratcorona; Montserrat Torrebadell; Mireia Camós; Josep Ll Aguilar; Jordi Esteve
Journal:  Blood       Date:  2010-12-23       Impact factor: 22.113

2.  Reproducibility and prognostic significance of morphologic dysplasia in de novo acute myeloid leukemia.

Authors:  Olga K Weinberg; Olga Pozdnyakova; Federico Campigotto; Daniel J DeAngelo; Richard M Stone; Donna Neuberg; Robert P Hasserjian
Journal:  Mod Pathol       Date:  2015-05-15       Impact factor: 7.842

3.  Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.

Authors:  Christopher J Gibson; R Coleman Lindsley; Vatche Tchekmedyian; Brenton G Mar; Jiantao Shi; Siddhartha Jaiswal; Alysia Bosworth; Liton Francisco; Jianbo He; Anita Bansal; Elizabeth A Morgan; Ann S Lacasce; Arnold S Freedman; David C Fisher; Eric Jacobsen; Philippe Armand; Edwin P Alyea; John Koreth; Vincent Ho; Robert J Soiffer; Joseph H Antin; Jerome Ritz; Sarah Nikiforow; Stephen J Forman; Franziska Michor; Donna Neuberg; Ravi Bhatia; Smita Bhatia; Benjamin L Ebert
Journal:  J Clin Oncol       Date:  2017-01-09       Impact factor: 44.544

4.  RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis.

Authors:  Susanne Schnittger; Frank Dicker; Wolfgang Kern; Nicole Wendland; Jana Sundermann; Tamara Alpermann; Claudia Haferlach; Torsten Haferlach
Journal:  Blood       Date:  2010-12-09       Impact factor: 22.113

Review 5.  The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia.

Authors:  Daniel A Arber; Attilio Orazi; Robert Hasserjian; Jürgen Thiele; Michael J Borowitz; Michelle M Le Beau; Clara D Bloomfield; Mario Cazzola; James W Vardiman
Journal:  Blood       Date:  2016-04-11       Impact factor: 22.113

6.  The new provisional WHO entity 'RUNX1 mutated AML' shows specific genetics but no prognostic influence of dysplasia.

Authors:  T Haferlach; A Stengel; S Eckstein; K Perglerová; T Alpermann; W Kern; C Haferlach; M Meggendorfer
Journal:  Leukemia       Date:  2016-05-23       Impact factor: 11.528
  6 in total
  2 in total

1.  High NPM1-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML.

Authors:  Sanjay S Patel; Frank C Kuo; Christopher J Gibson; David P Steensma; Robert J Soiffer; Edwin P Alyea; Yi-Bin A Chen; Amir T Fathi; Timothy A Graubert; Andrew M Brunner; Martha Wadleigh; Richard M Stone; Daniel J DeAngelo; Valentina Nardi; Robert P Hasserjian; Olga K Weinberg
Journal:  Blood       Date:  2018-05-03       Impact factor: 22.113

2.  Association of mutations with morphological dysplasia in de novo acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities.

Authors:  Olga K Weinberg; Christopher J Gibson; Traci M Blonquist; Donna Neuberg; Olga Pozdnyakova; Frank Kuo; Benjamin L Ebert; Robert P Hasserjian
Journal:  Haematologica       Date:  2018-01-11       Impact factor: 9.941
  2 in total

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