| Literature DB >> 2836997 |
T Kumanomido1, R Wada, T Kanemaru, M Kamada, K Hirasawa, Y Akiyama.
Abstract
The pathogenicity of Getah virus for swine was examined. All 8 pigs (4 adults and 4 piglets) inoculated with Strains MIP-99 and MI-110 developed pyrexia ranging from 39.4 to 40.7 degrees C and anorexia. Mild depression and diarrhea were observed in 2 of the 4 piglets. These clinical signs were transient. Viremia occurred 1-2 days post-inoculation (p.i.) and the maximum titer was 10(3.0) TCID50 0.1 ml-1. The virus was recovered from a piglet autopsied on Day 3 p.i. from spleen and various lymph nodes. The maximum titer of virus (10(3.75) TCID50 0.1 g-1) was detected in the inguinal lymph node. Seroconversion was demonstrated in all the pigs on Day 6 p.i. These results suggest that Getah virus is mildly pathogenic for swine, which may play a role as an amplifying host in nature.Entities:
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Year: 1988 PMID： 2836997 DOI： 10.1016/0378-1135(88)90033-8
Source DB: PubMed Journal: Vet Microbiol ISSN： 0378-1135 Impact factor: 3.293