Christianne Micallef1,2, Navila T Chaudhry3,4, Alison H Holmes1,5, Susan Hopkins1,6, Jonathan Benn4, Bryony Dean Franklin1,3,4,7. 1. NIHR Health Protection Research Unit, Healthcare Associated Infection and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, London, UK. 2. Pharmacy Department, Addenbrooke`s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. 3. Centre for Medication Safety and Service Quality, Imperial College Healthcare NHS Trust, London, UK. 4. NIHR Imperial Patient Safety Translational Research Centre, Imperial College London, London, UK. 5. Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK. 6. Public Health England, London, UK. 7. Research Department of Practice and Policy, UCL School of Pharmacy, Mezzanine Floor, BMA House, Tavistock Square, London, UK.
Abstract
Background: Electronic prescribing (EP) and electronic hospital pharmacy (EHP) systems are increasingly common. A potential benefit is the extensive data in these systems that could be used to support antimicrobial stewardship, but there is little information on how such data are currently used to support the quality and safety of antimicrobial use. Objectives: To summarize the literature on secondary use of data (SuD) from EP and EHP systems to support quality and safety of antimicrobial use, to describe any barriers to secondary use and to make recommendations for future work in this field. Methods: We conducted a systematic search within four databases; we included original research studies that were (1) based on SuD from hospital EP or EHP systems and (2) reported outcomes relating to quality and/or safety of antimicrobial use and/or qualitative findings relating to SuD in this context. Results: Ninety-four full-text articles were obtained; 14 met our inclusion criteria. Only two described interventions based on SuD; seven described SuD to evaluate other antimicrobial stewardship interventions and five described descriptive or exploratory studies of potential applications of SuD. Types of data used were quantitative antibiotic usage data ( n = 9 studies), dose administration data ( n = 4) and user log data from an electronic dashboard ( n = 1). Barriers included data access, data accuracy and completeness, and complexity when using data from multiple systems or hospital sites. Conclusions: The literature suggests that SuD from EP and EHP systems is potentially useful to support or evaluate antimicrobial stewardship activities; greater system functionality would help to realize these benefits.
Background: Electronic prescribing (EP) and electronic hospital pharmacy (EHP) systems are increasingly common. A potential benefit is the extensive data in these systems that could be used to support antimicrobial stewardship, but there is little information on how such data are currently used to support the quality and safety of antimicrobial use. Objectives: To summarize the literature on secondary use of data (SuD) from EP and EHP systems to support quality and safety of antimicrobial use, to describe any barriers to secondary use and to make recommendations for future work in this field. Methods: We conducted a systematic search within four databases; we included original research studies that were (1) based on SuD from hospital EP or EHP systems and (2) reported outcomes relating to quality and/or safety of antimicrobial use and/or qualitative findings relating to SuD in this context. Results: Ninety-four full-text articles were obtained; 14 met our inclusion criteria. Only two described interventions based on SuD; seven described SuD to evaluate other antimicrobial stewardship interventions and five described descriptive or exploratory studies of potential applications of SuD. Types of data used were quantitative antibiotic usage data ( n = 9 studies), dose administration data ( n = 4) and user log data from an electronic dashboard ( n = 1). Barriers included data access, data accuracy and completeness, and complexity when using data from multiple systems or hospital sites. Conclusions: The literature suggests that SuD from EP and EHP systems is potentially useful to support or evaluate antimicrobial stewardship activities; greater system functionality would help to realize these benefits.
Authors: J Keizer; L M A Braakman-Jansen; S Kampmeier; R Köck; N Al Naiemi; R Te Riet-Warning; N Beerlage-De Jong; K Becker; J E W C Van Gemert-Pijnen Journal: Antimicrob Resist Infect Control Date: 2019-07-22 Impact factor: 4.887
Authors: J Keizer; N Beerlage-De Jong; N Al Naiemi; J E W C van Gemert-Pijnen Journal: Antimicrob Resist Infect Control Date: 2020-08-05 Impact factor: 4.887
Authors: P F Dutey-Magni; M J Gill; D McNulty; G Sohal; A Hayward; L Shallcross; Niall Anderson; Elise Crayton; Gillian Forbes; Arnoupe Jhass; Emma Richardson; Michelle Richardson; Patrick Rockenschaub; Catherine Smith; Elizabeth Sutton; Rosanna Traina; Lou Atkins; Anne Conolly; Spiros Denaxas; Ellen Fragaszy; Rob Horne; Patty Kostkova; Fabiana Lorencatto; Susan Michie; Jennifer Mindell; John Robson; Claire Royston; Carolyn Tarrant; James Thomas; Jonathan West; Haydn Williams; Nadia Elsay; Chris Fuller Journal: JAC Antimicrob Resist Date: 2021-03-04