| Literature DB >> 28369258 |
Yuka Nakai1, Akihisa Ito1, Yohsuke Ogawa1, Swarmistha Devi Aribam1, Marta Elsheimer-Matulova1, Kazumasa Shiraiwa1, Stevens M B Kisaka1, Hirokazu Hikono1, Sayaka Nishikawa1, Masato Akiba1, Kazuyoshi Kawahara2, Yoshihiro Shimoji1, Masahiro Eguchi1.
Abstract
Salmonella enterica serovar Typhimurium (S. Typhimurium) has two serological variants: one that expresses the O:5 antigen (1,4,5,12:i:1,2) and one that lacks O:5 antigen (1,4,12:i:1,2). For serotyping, S. Typhimurium is agglutinated by diagnostic O:4 antigen serum. This study was carried out to compare the antigen-antibody affinity of O:4 antigen in S. Typhimurium χ3306 O:5-positive and S. Typhimurium χ3306 O:5-negative strains. The affinity of O:4 antigen with O:4 antigen serum was found to be stronger in the O:5-negative strains compared to O:5-positive strains. Next, we investigated the antigen-antibody affinity of O:4 antigen with O:4 antigen serum in field strains of S. Typhimurium, which showed the same tendency in affinity as seen with S. Typhimurium χ3306 O:5-positive and negative strains. This study suggests that the presence or absence of O:5 antigen causes differences in O:4 agglutination reactions with different field strains of S. Typhimurium. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.Entities:
Keywords: O:5 antigen; Salmonella enterica serovar Typhimurium; microagglutination test; serodiagnosis
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Year: 2017 PMID： 28369258 DOI： 10.1093/femsle/fnx062
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742