Literature DB >> 28369015

Nipple-Areola Complex Malposition in Nipple-Sparing Mastectomy: A Review of Risk Factors and Corrective Techniques from Greater than 1000 Reconstructions.

Mihye Choi1,2, Jordan D Frey1,2, Ara A Salibian1,2, Nolan S Karp1,2.   

Abstract

BACKGROUND: Nipple-areola complex malposition after nipple-sparing mastectomy can be a challenging issue to correct. The current literature is largely limited to smaller series and implant-based reconstructions.
METHODS: A retrospective review of all nipple-sparing mastectomies from 2006 to 2016 at a single institution was performed. Incidence, risk factors, and corrective techniques of nipple-areola complex malposition were analyzed.
RESULTS: One thousand thirty-seven cases of nipple-sparing mastectomy were identified, of which 77 (7.4 percent) underwent nipple-areola complex repositioning. All were performed in a delayed fashion. The most common techniques included crescentic periareolar excision [n = 25 (32.5 percent)] and directional skin excision [n = 10 (13.0 percent)]. Cases requiring nipple-areola complex repositioning were significantly more likely to have preoperative radiation therapy (p = 0.0008), a vertical or Wise pattern incision (p = 0.0157), autologous reconstruction (p = 0.0219), and minor mastectomy flap necrosis (p = 0.0462). Previous radiation therapy (OR, 3.6827; p = 0.0028), vertical radial mastectomy incisions (OR, 1.8218; p = 0.0202), and autologous reconstruction (OR, 1.77; p = 0.0053) were positive independent predictors of nipple-areola complex repositioning, whereas implant-based reconstruction (OR, 0.5552; p < 0.0001) was a negative independent predictor of repositioning. Body mass index (p = 0.7104) and adjuvant radiation therapy (p = 0.9536), among other variables, were not predictors of nipple-areola complex repositioning.
CONCLUSIONS: Nipple-areola complex malposition after nipple-sparing mastectomy can be successfully corrected with various techniques. Previous radiation therapy, vertical mastectomy incisions, and autologous reconstruction are independently predictive of nipple-areola complex malposition. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.

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Year:  2017        PMID: 28369015     DOI: 10.1097/PRS.0000000000003507

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  11 in total

1.  Nipple-Sparing Mastectomy Incisions for Cancer Extirpation Prospective Cohort Trial: Perfusion, Complications, and Patient Outcomes.

Authors:  Elizabeth B Odom; Rajiv P Parikh; Grace Um; Simone W Kantola; Amy E Cyr; Julie A Margenthaler; Marissa M Tenenbaum; Terence M Myckatyn
Journal:  Plast Reconstr Surg       Date:  2018-07       Impact factor: 4.730

Review 2.  Implant Reconstruction in Nipple Sparing Mastectomy.

Authors:  Carrie K Chu; Matthew J Davis; Amjed Abu-Ghname; Sebastian J Winocour; Albert Losken; Grant W Carlson
Journal:  Semin Plast Surg       Date:  2019-10-17       Impact factor: 2.314

Review 3.  Chest Feminization in Male-to-Female Transgender Patients: A Review of Options.

Authors:  Harsh Patel; Yasmina Samaha; Graham Ives; Tian-Yu Lee; Xiaojiang Cui; Edward Ray
Journal:  Transgend Health       Date:  2021-10-04

4.  Mastectomy Incision Design to Optimize Aesthetic Outcomes in Breast Reconstruction.

Authors:  Adi Maisel Lotan; Krystina C Tongson; Alice M Police; Wojciech Dec
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-09-24

5.  Nipple-sparing mastectomy with immediate breast reconstruction - early complications and outcomes of the treatment.

Authors:  Artur Bocian; Piotr Kędzierawski; Krzysztof Kurczych; Przemysław Jasnowski; Daniel Maliszewski; Agnieszka Kołacińska
Journal:  Prz Menopauzalny       Date:  2020-10-02

6.  Modified C-H flap for simultaneous nipple reconstruction during autologous breast reconstruction: Surgical tips for safety and cosmesis.

Authors:  Jung Soo Yoon; Jung Woo Chang; Hee Chang Ahn; Min Sung Chung
Journal:  Medicine (Baltimore)       Date:  2018-09       Impact factor: 1.817

7.  Current surgical practices of robotic-assisted tissue repair and reconstruction.

Authors:  Peng Wang; Ying-Jun Su; Chi-Yu Jia
Journal:  Chin J Traumatol       Date:  2019-02-27

8.  Breast Splint for Prevention of Nipple-areolar Complex Malposition after Direct-to-implant Breast Reconstruction.

Authors:  Yoshihiro Sowa; Takuya Kodama; Yuko Fuchinoue; Naoki Inafuku; Yasunobu Terao
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-01-03

9.  Satisfaction with Long-Term Aesthetic and 10 Years Oncologic Outcome following Risk-Reducing Mastectomy and Implant-Based Breast Reconstruction with or without Nipple Preservation.

Authors:  Rachel Louise O'Connell; Marios Konstantinos Tasoulis; Evguenia Hristova; Victoria Teoh; Ana Agusti; Ann Ward; Catherine Montgomery; Kabir Mohammed; Janet Self; Jennifer Elizabeth Rusby; Gerald Gui
Journal:  Cancers (Basel)       Date:  2022-07-24       Impact factor: 6.575

10.  Identification of Independent Risk Factors for Skin Complications in a Multifactorial Logistic Regression Analysis of Simultaneous Immediate Autologous Breast Reconstruction and Skin Reduction Mastectomy in Large and Ptotic Breasts Using an Inferiorly Based Deepithelialized Dermal Breast Flap.

Authors:  Felix H Vollbach; Benjamin F Thomas; Hisham Fansa
Journal:  J Pers Med       Date:  2022-02-23
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