OBJECTIVE: Individuals with schizophrenia demonstrate cognitive, social cognitive, and motivational deficits that contribute to impairment in real-world functioning. In the current study, we investigated the effects of supplementing computerized neurocognitive training with social cognitive exercises, as compared with neurocognitive training alone. METHOD: In this ongoing, double-blind, randomized controlled trial of 111 participants with psychosis, we compare the effects of supplementing intensive targeted cognitive training with social cognitive training exercises (TCT + SCT) with the effects of targeted cognitive training alone (TCT-only). Participants were assessed on cognition, symptoms, functional capacity, and functional outcomes, as well as social cognition and measures related to reward processing. RESULTS: Both treatment groups showed significant improvement in multiple cognitive domains and improvement in functional capacity. However, as predicted, TCT + SCT group participants showed significant improvement in prosody identification and reward processing relative to TCT-only participants. CONCLUSIONS AND IMPLICATIONS FOR PRACTICE: Our findings indicate that supplementing intensive computerized cognitive training with social cognitive exercises in people with psychosis confers greater benefits in prosody identification and reward processing relative to cognitive training alone, even though both approaches drive significant improvements in cognition and functional capacity. Impairments in both prosody identification and reward processing have been associated with greater negative symptoms and poorer functional outcomes in schizophrenia, raising the possibility that this form of treatment may lead to better long-term outcomes than traditional cognitive training approaches. Follow-up assessments will determine whether results are durable and generalize over time to improvements in symptoms and functioning. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
RCT Entities:
OBJECTIVE: Individuals with schizophrenia demonstrate cognitive, social cognitive, and motivational deficits that contribute to impairment in real-world functioning. In the current study, we investigated the effects of supplementing computerized neurocognitive training with social cognitive exercises, as compared with neurocognitive training alone. METHOD: In this ongoing, double-blind, randomized controlled trial of 111 participants with psychosis, we compare the effects of supplementing intensive targeted cognitive training with social cognitive training exercises (TCT + SCT) with the effects of targeted cognitive training alone (TCT-only). Participants were assessed on cognition, symptoms, functional capacity, and functional outcomes, as well as social cognition and measures related to reward processing. RESULTS: Both treatment groups showed significant improvement in multiple cognitive domains and improvement in functional capacity. However, as predicted, TCT + SCT group participants showed significant improvement in prosody identification and reward processing relative to TCT-only participants. CONCLUSIONS AND IMPLICATIONS FOR PRACTICE: Our findings indicate that supplementing intensive computerized cognitive training with social cognitive exercises in people with psychosis confers greater benefits in prosody identification and reward processing relative to cognitive training alone, even though both approaches drive significant improvements in cognition and functional capacity. Impairments in both prosody identification and reward processing have been associated with greater negative symptoms and poorer functional outcomes in schizophrenia, raising the possibility that this form of treatment may lead to better long-term outcomes than traditional cognitive training approaches. Follow-up assessments will determine whether results are durable and generalize over time to improvements in symptoms and functioning. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Authors: Jiao Wang; Jia Huang; Xin-Hua Yang; Simon S Y Lui; Eric F C Cheung; Raymond C K Chan Journal: Schizophr Res Date: 2015-07-14 Impact factor: 4.939
Authors: Haralahalli D Bhagyavathi; Urvakhsh Meherwan Mehta; Jagadisha Thirthalli; C Naveen Kumar; J Keshav Kumar; D K Subbakrishna; Bangalore N Gangadhar Journal: Psychiatry Res Date: 2015-07-16 Impact factor: 3.222
Authors: Mor Nahum; Hyunkyu Lee; Melissa Fisher; Michael F Green; Christine I Hooker; Joseph Ventura; Joshua T Jordan; Annika Rose; Sarah-Jane Kim; Kristen M Haut; Michael M Merzenich; Sophia Vinogradov Journal: Schizophr Bull Date: 2021-01-23 Impact factor: 9.306
Authors: Pamela D Butler; Matthew J Hoptman; David V Smith; Julia A Ermel; Daniel J Calderone; Sang Han Lee; Deanna M Barch Journal: J Psychiatr Brain Sci Date: 2020-02-27
Authors: Kathleen Miley; Melissa Fisher; Mor Nahum; Elizabeth Howard; Abby Rowlands; Benjamin Brandrett; Josh Woolley; Christine I Hooker; Bruno Biagianti; Ian Ramsay; Sophia Vinogradov Journal: Schizophr Res Cogn Date: 2019-12-26