Literature DB >> 28366934

Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape.

P Silva1, M Neumann1,2,3, M P Schroeder1, S Vosberg2,3,4, C Schlee1, K Isaakidis1, J Ortiz-Tanchez1, L R Fransecky1, T Hartung1, S Türkmen5,6, A Graf7, S Krebs7, H Blum7, C Müller-Tidow8, C Thiede2,3,9, G Ehninger2,3,9, H Serve2,3,10, J Hecht11,12, W E Berdel13, P A Greif2,3,4, C Röllig2,3,9, C D Baldus1,2,3.   

Abstract

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Year:  2017        PMID： 28366934     DOI： 10.1038/leu.2017.109

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  15 in total

1.  Genomic Classification and Prognosis in Acute Myeloid Leukemia.

Authors:  Elli Papaemmanuil; Moritz Gerstung; Hartmut Döhner; Peter J Campbell; Lars Bullinger; Verena I Gaidzik; Peter Paschka; Nicola D Roberts; Nicola E Potter; Michael Heuser; Felicitas Thol; Niccolo Bolli; Gunes Gundem; Peter Van Loo; Inigo Martincorena; Peter Ganly; Laura Mudie; Stuart McLaren; Sarah O'Meara; Keiran Raine; David R Jones; Jon W Teague; Adam P Butler; Mel F Greaves; Arnold Ganser; Konstanze Döhner; Richard F Schlenk
Journal:  N Engl J Med       Date:  2016-06-09       Impact factor: 91.245

2.  DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.

Authors:  Olga A Guryanova; Kaitlyn Shank; Barbara Spitzer; Luisa Luciani; Richard P Koche; Francine E Garrett-Bakelman; Chezi Ganzel; Benjamin H Durham; Abhinita Mohanty; Gregor Hoermann; Sharon A Rivera; Alan G Chramiec; Elodie Pronier; Lennart Bastian; Matthew D Keller; Daniel Tovbin; Evangelia Loizou; Abby R Weinstein; Adriana Rodriguez Gonzalez; Yen K Lieu; Jacob M Rowe; Friederike Pastore; Anna Sophia McKenney; Andrei V Krivtsov; Wolfgang R Sperr; Justin R Cross; Christopher E Mason; Martin S Tallman; Maria E Arcila; Omar Abdel-Wahab; Scott A Armstrong; Stefan Kubicek; Philipp B Staber; Mithat Gönen; Elisabeth M Paietta; Ari M Melnick; Stephen D Nimer; Siddhartha Mukherjee; Ross L Levine
Journal:  Nat Med       Date:  2016-11-14       Impact factor: 53.440

3.  TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics.

Authors:  Wen-Chien Chou; Sheng-Chieh Chou; Chieh-Yu Liu; Chien-Yuan Chen; Hsin-An Hou; Yuan-Yeh Kuo; Ming-Cheng Lee; Bor-Sheng Ko; Jih-Luh Tang; Ming Yao; Woei Tsay; Shang-Ju Wu; Shang-Yi Huang; Szu-Chun Hsu; Yao-Chang Chen; Yi-Chang Chang; Yi-Yi Kuo; Kuan-Ting Kuo; Fen-Yu Lee; Ming-Chi Liu; Chia-Wen Liu; Mei-Hsuan Tseng; Chi-Fei Huang; Hwei-Fang Tien
Journal:  Blood       Date:  2011-08-09       Impact factor: 22.113

4.  RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes.

Authors:  Philipp A Greif; Nikola P Konstandin; Klaus H Metzeler; Tobias Herold; Zlatana Pasalic; Bianka Ksienzyk; Annika Dufour; Friederike Schneider; Stephanie Schneider; Purvi M Kakadia; Jan Braess; Maria Cristina Sauerland; Wolfgang E Berdel; Thomas Büchner; Bernhard J Woermann; Wolfgang Hiddemann; Karsten Spiekermann; Stefan K Bohlander
Journal:  Haematologica       Date:  2012-06-11       Impact factor: 9.941

5.  Characterization and prognostic features of secondary acute myeloid leukemia in a population-based setting: a report from the Swedish Acute Leukemia Registry.

Authors:  Erik Hulegårdh; Christer Nilsson; Vladimir Lazarevic; Hege Garelius; Petar Antunovic; Åsa Rangert Derolf; Lars Möllgård; Bertil Uggla; Lovisa Wennström; Anders Wahlin; Martin Höglund; Gunnar Juliusson; Dick Stockelberg; Sören Lehmann
Journal:  Am J Hematol       Date:  2015-01-16       Impact factor: 10.047

6.  Frequent pathway mutations of splicing machinery in myelodysplasia.

Authors:  Kenichi Yoshida; Masashi Sanada; Yuichi Shiraishi; Daniel Nowak; Yasunobu Nagata; Ryo Yamamoto; Yusuke Sato; Aiko Sato-Otsubo; Ayana Kon; Masao Nagasaki; George Chalkidis; Yutaka Suzuki; Masashi Shiosaka; Ryoichiro Kawahata; Tomoyuki Yamaguchi; Makoto Otsu; Naoshi Obara; Mamiko Sakata-Yanagimoto; Ken Ishiyama; Hiraku Mori; Florian Nolte; Wolf-Karsten Hofmann; Shuichi Miyawaki; Sumio Sugano; Claudia Haferlach; H Phillip Koeffler; Lee-Yung Shih; Torsten Haferlach; Shigeru Chiba; Hiromitsu Nakauchi; Satoru Miyano; Seishi Ogawa
Journal:  Nature       Date:  2011-09-11       Impact factor: 49.962

7.  Age-related risk profile and chemotherapy dose response in acute myeloid leukemia: a study by the German Acute Myeloid Leukemia Cooperative Group.

Authors:  Thomas Büchner; Wolfgang E Berdel; Claudia Haferlach; Torsten Haferlach; Susanne Schnittger; Carsten Müller-Tidow; Jan Braess; Karsten Spiekermann; Joachim Kienast; Peter Staib; Andreas Grüneisen; Wolfgang Kern; Albrecht Reichle; Georg Maschmeyer; Carlo Aul; Eva Lengfelder; Maria-Cristina Sauerland; Achim Heinecke; Bernhard Wörmann; Wolfgang Hiddemann
Journal:  J Clin Oncol       Date:  2008-12-01       Impact factor: 44.544

8.  MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation.

Authors:  Maria E Figueroa; Lucy Skrabanek; Yushan Li; Anchalee Jiemjit; Tamer E Fandy; Elisabeth Paietta; Hugo Fernandez; Martin S Tallman; John M Greally; Hetty Carraway; Jonathan D Licht; Steven D Gore; Ari Melnick
Journal:  Blood       Date:  2009-08-03       Impact factor: 22.113

9.  Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.

Authors:  Klaus H Metzeler; Tobias Herold; Maja Rothenberg-Thurley; Susanne Amler; Maria C Sauerland; Dennis Görlich; Stephanie Schneider; Nikola P Konstandin; Annika Dufour; Kathrin Bräundl; Bianka Ksienzyk; Evelyn Zellmeier; Luise Hartmann; Philipp A Greif; Michael Fiegl; Marion Subklewe; Stefan K Bohlander; Utz Krug; Andreas Faldum; Wolfgang E Berdel; Bernhard Wörmann; Thomas Büchner; Wolfgang Hiddemann; Jan Braess; Karsten Spiekermann
Journal:  Blood       Date:  2016-06-10       Impact factor: 22.113

10.  Epigenetic Aging Signatures Are Coherently Modified in Cancer.

Authors:  Qiong Lin; Wolfgang Wagner
Journal:  PLoS Genet       Date:  2015-06-25       Impact factor: 5.917
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  13 in total

1.  Profiling the Effect of Targeting Wild Isocitrate Dehydrogenase 1 (IDH1) on the Cellular Metabolome of Leukemic Cells.

Authors:  Mohammed Razeeth Shait Mohammed; Faisal Alzahrani; Salman Hosawi; Hani Choudhry; Mohammad Imran Khan
Journal:  Int J Mol Sci       Date:  2022-06-15       Impact factor: 6.208

Review 2.  Clinical developments in epigenetic-directed therapies in acute myeloid leukemia.

Authors:  Darren Pan; Raajit Rampal; John Mascarenhas
Journal:  Blood Adv       Date:  2020-03-10

3.  The Impact of DNMT3A Status on NPM1 MRD Predictive Value and Survival in Elderly AML Patients Treated Intensively.

Authors:  Heiblig Maël; Duployez Nicolas; Marceau Alice; Lebon Delphine; Goursaud Laure; Plantier Isabelle; Stalnikiewich Laure; Cambier Nathalie; Balsat Marie; Fossard Gaëlle; Labussière-Wallet Hélène; Barraco Fiorenza; Ducastelle-Lepretre Sophie; Sujobert Pierre; Huet Sarah; Hayette Sandrine; Ghesquières Hervé; Thomas Xavier; Preudhomme Claude
Journal:  Cancers (Basel)       Date:  2021-04-29       Impact factor: 6.639

4.  Mutational features of myelodysplastic syndromes with Auer rods reveal them are more akin to acute myeloid leukemia.

Authors:  Huijun Huang; Tiejun Qin; Zefeng Xu; Zhongxun Shi; Bing Li; Lijuan Pan; Naibo Hu; Shiqiang Qu; Gang Huang; Robert P Gale; Zhijian Xiao
Journal:  Br J Haematol       Date:  2019-12-27       Impact factor: 8.615

Review 5.  Chromosomal Instability in Acute Myeloid Leukemia.

Authors:  Mateus de Oliveira Lisboa; Paulo Roberto Slud Brofman; Ana Teresa Schmid-Braz; Aline Rangel-Pozzo; Sabine Mai
Journal:  Cancers (Basel)       Date:  2021-05-28       Impact factor: 6.639

6.  Clinical features and biological implications of different U2AF1 mutation types in myelodysplastic syndromes.

Authors:  Bing Li; Jinqin Liu; Yujiao Jia; Jingya Wang; Zefeng Xu; Tiejun Qin; Zhongxun Shi; Zhen Song; Shuailing Peng; Huijun Huang; Liwei Fang; Hongli Zhang; Lijuan Pan; Naibo Hu; Shiqiang Qu; Yue Zhang; Jian Wu; Na Liu; Kun Ru; Gang Huang; Zhijian Xiao
Journal:  Genes Chromosomes Cancer       Date:  2017-11-23       Impact factor: 4.263

7.  Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older.

Authors:  Victoria V Prassek; Maja Rothenberg-Thurley; Maria C Sauerland; Tobias Herold; Hanna Janke; Bianka Ksienzyk; Nikola P Konstandin; Dennis Goerlich; Utz Krug; Andreas Faldum; Wolfgang E Berdel; Bernhard Wörmann; Jan Braess; Stephanie Schneider; Marion Subklewe; Stefan K Bohlander; Wolfgang Hiddemann; Karsten Spiekermann; Klaus H Metzeler
Journal:  Haematologica       Date:  2018-06-14       Impact factor: 9.941

8.  Next-Generation Sequencing Improves Diagnosis, Prognosis and Clinical Management of Myeloid Neoplasms.

Authors:  Diego Carbonell; Julia Suárez-González; María Chicano; Cristina Andrés-Zayas; Juan Carlos Triviño; Gabriela Rodríguez-Macías; Mariana Bastos-Oreiro; Patricia Font; Mónica Ballesteros; Paula Muñiz; Pascual Balsalobre; Mi Kwon; Javier Anguita; José Luis Díez-Martín; Ismael Buño; Carolina Martínez-Laperche
Journal:  Cancers (Basel)       Date:  2019-09-13       Impact factor: 6.639

Review 9.  Acute Myeloid Leukemia: Aging and Epigenetics.

Authors:  Polina Zjablovskaja; Maria Carolina Florian
Journal:  Cancers (Basel)       Date:  2019-12-31       Impact factor: 6.639

10.  A deconvolution method and its application in analyzing the cellular fractions in acute myeloid leukemia samples.

Authors:  Huamei Li; Amit Sharma; Wenglong Ming; Xiao Sun; Hongde Liu
Journal:  BMC Genomics       Date:  2020-09-23       Impact factor: 3.969
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