Literature DB >> 2836628

Subcellular localization of the human immunodeficiency virus trans-acting art gene product.

B R Cullen1, J Hauber, K Campbell, J G Sodroski, W A Haseltine, C A Rosen.   

Abstract

The genome of the human immunodeficiency virus is distinguished from other animal retroviruses by the presence of several additional open reading frames. The protein product of one of these novel genes, which has been termed art or trs, is required for the expression of the virus structural genes but not for the expression of virus encoded regulatory proteins. Immunocytochemistry and subcellular fractionation demonstrate that the art protein is located predominantly in the nucleus. Therefore, any proposed mechanism for the function of art is likely to involve nuclear events.

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Year:  1988        PMID： 2836628      PMCID： PMC253409          DOI： 10.1128/JVI.62.7.2498-2501.1988

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  The trans-activator gene of the human T cell lymphotropic virus type III is required for replication.

Authors:  A I Dayton; J G Sodroski; C A Rosen; W C Goh; W A Haseltine
Journal:  Cell       Date:  1986-03-28       Impact factor: 41.582

2.  The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat.

Authors:  C A Rosen; J G Sodroski; W A Haseltine
Journal:  Cell       Date:  1985-07       Impact factor: 41.582

3.  Location of the trans-activating region on the genome of human T-cell lymphotropic virus type III.

Authors:  J Sodroski; R Patarca; C Rosen; F Wong-Staal; W Haseltine
Journal:  Science       Date:  1985-07-05       Impact factor: 47.728

4.  Post-transcriptional regulation accounts for the trans-activation of the human T-lymphotropic virus type III.

Authors:  C A Rosen; J G Sodroski; W C Goh; A I Dayton; J Lippke; W A Haseltine
Journal:  Nature       Date:  1986 Feb 13-19       Impact factor: 49.962

5.  Construction of recombinant murine retroviruses that express the human T-cell leukemia virus type II and human T-cell lymphotropic virus type III trans activator genes.

Authors:  C A Rosen; J G Sodroski; K Campbell; W A Haseltine
Journal:  J Virol       Date:  1986-01       Impact factor: 5.103

6.  Use of eukaryotic expression technology in the functional analysis of cloned genes.

Authors:  B R Cullen
Journal:  Methods Enzymol       Date:  1987       Impact factor: 1.600

7.  Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus.

Authors:  C A Rosen; E Terwilliger; A Dayton; J G Sodroski; W A Haseltine
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

8.  Subcellular localization of the product of the long open reading frame of human T-cell leukemia virus type I.

Authors:  W C Goh; J Sodroski; C Rosen; M Essex; W A Haseltine
Journal:  Science       Date:  1985-03-08       Impact factor: 47.728

9.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

10.  Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).

Authors:  S K Arya; C Guo; S F Josephs; F Wong-Staal
Journal:  Science       Date:  1985-07-05       Impact factor: 47.728
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  60 in total

1.  FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles.

Authors:  P Shannon Pendergrast; Chen Wang; Nouria Hernandez; Sui Huang
Journal:  Mol Biol Cell       Date:  2002-03       Impact factor: 4.138

2.  A nucleolar TAR decoy inhibitor of HIV-1 replication.

Authors:  Alessandro Michienzi; Shirley Li; John A Zaia; John J Rossi
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-10       Impact factor: 11.205

3.  Human immunodeficiency virus type 1 Rev activation can be achieved without Rev-responsive element RNA if Rev is directed to the target as a Rev/MS2 fusion protein which tethers the MS2 operator RNA.

Authors:  S Venkatesan; S M Gerstberger; H Park; S M Holland; Y Nam
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

4.  trans-dominant inhibition of human immunodeficiency virus type 1 Rev occurs through formation of inactive protein complexes.

Authors:  T J Hope; N P Klein; M E Elder; T G Parslow
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

5.  Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1.

Authors:  L Solomin; B K Felber; G N Pavlakis
Journal:  J Virol       Date:  1990-12       Impact factor: 5.103

6.  Human immunodeficiency virus rev protein recognizes a target sequence in rev-responsive element RNA within the context of RNA secondary structure.

Authors:  S M Holland; N Ahmad; R K Maitra; P Wingfield; S Venkatesan
Journal:  J Virol       Date:  1990-12       Impact factor: 5.103

7.  Mutational definition of the human immunodeficiency virus type 1 Rev activation domain.

Authors:  M H Malim; D F McCarn; L S Tiley; B R Cullen
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

8.  Rev-dependent expression of human immunodeficiency virus type 1 gp160 in Drosophila melanogaster cells.

Authors:  M Ivey-Hoyle; M Rosenberg
Journal:  Mol Cell Biol       Date:  1990-12       Impact factor: 4.272

9.  Nucleolar localization of myc transcripts.

Authors:  V C Bond; B Wold
Journal:  Mol Cell Biol       Date:  1993-06       Impact factor: 4.272

10.  Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export.

Authors:  D C Love; T D Sweitzer; J A Hanover
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205
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