Literature DB >> 28365857

A case report of atypical long segmental thoracic hypertrophic pachymeningitis with ossification of ligamentum flavum and literature review.

Ruofu Tang1, Fangcai Li2, Qixin Chen2.   

Abstract

BACKGROUND: Thoracic spinal stenosis caused by ossification of ligamentum flavum (OLF) is frequently seen, but long segmental thoracic spinal cord compressed by consequent thickened ligament posteriorly was rarely reported. OBJECT: To report a case of thoracic spinal cord compression caused by atypical long segmental thoracic hypertrophic pachymeningitis (HP) with OLF.
METHODS: A 55-year-old woman presenting with weakness and numbness in lower extremities was admitted to our department. Combined with physical examination and MRI results, diagnosis of HP with OLF was considered. Due to progressive neurological symptoms, thoracic decompression with internal fixation was performed.
RESULTS: The patient felt a reduced numbness and improvement in motor functions 5 days after surgery. Pathological examination suggested the diagnosis of HP with OLF.
CONCLUSIONS: HP is a rare condition characterized as thickening and enhancement of the dura mater on contrast-enhanced MRI and chronic inflammatory hyperplasia changes on biopsy. A case of atypical HP complicated with OLF is described. Chondrocytes infiltration in histological examination indicates the potential of ossification in HP.

Entities:  

Keywords:  Hypertrophic pachymeningitis; Myelopathy; Ossification of ligamentum flavum; Thoracic spine

Mesh:

Year:  2017        PMID: 28365857     DOI: 10.1007/s00586-017-5030-x

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  37 in total

1.  Idiopathic hypertrophic pachymeningitis successfully treated with intravenous cyclophosphamide.

Authors:  Chen Zhuoyou; Qian Chuanzhong; Ding Xinsheng
Journal:  Neurol India       Date:  2011 Nov-Dec       Impact factor: 2.117

2.  Optic perineuritis associated with antineutrophil cytoplasmic autoantibody-related hypertrophic pachymeningitis: a case report.

Authors:  Hideto Nakajima; Kazushi Yamane; Fumiharu Kimura; Hidehiro Oku
Journal:  Neurol Sci       Date:  2015-12-22       Impact factor: 3.307

3.  Immunoglobulin g4-related hypertrophic pachymeningitis with skull involvement.

Authors:  Young-Sub Lee; Hye Won Lee; Ki-Su Park; Seong-Hyun Park; Jeong-Hyun Hwang
Journal:  Brain Tumor Res Treat       Date:  2014-10-31

4.  Hypertrophic cervical spinal cord pachymeningitis due to Treponema pallidum infection.

Authors:  Thiago Cardoso Vale; Thales Eduardo Caldeira Moraes; Amanda Lara; Gláucia Fernandes Cota; Paulo Pereira Christo
Journal:  Neurol Sci       Date:  2011-08-24       Impact factor: 3.307

5.  Multifocal fibrosclerosis. Report of a case of bilateral idiopathic sclerosing pseudotumor and retroperitoneal fibrosis.

Authors:  M R Levine; L Kaye; S Mair; J Bates
Journal:  Arch Ophthalmol       Date:  1993-06

6.  Idiopathic hypertrophic cranial pachymeningitis successfully treated with weekly subcutaneous methotrexate.

Authors:  J L Ruiz-Sandoval; G Bernard-Medina; E J Ramos-Gómez; S Romero-Vargas; S Gutiérrez-Ureña; S González-Cornejo; E Chiquete
Journal:  Acta Neurochir (Wien)       Date:  2006-04-18       Impact factor: 2.216

7.  Petriellidium boydii pachymeningitis treated with miconazole and ketoconazole.

Authors:  R J Schiess; M F Coscia; G A McClellan
Journal:  Neurosurgery       Date:  1984-02       Impact factor: 4.654

8.  [A case of hypertrophic pachymeningitis treated successfully with antibiotics: the remarkable effect of minocycline hydrochloride in reducing the serum C-reactive protein value].

Authors:  Makoto Kanai; Hiroshi Shimizu
Journal:  No Shinkei Geka       Date:  2009-07

9.  Thoracic ossification of the human ligamentum flavum: histopathological and immunohistochemical findings around the ossified lesion.

Authors:  Takafumi Yayama; Kenzo Uchida; Shigeru Kobayashi; Yasuo Kokubo; Ryuichiro Sato; Hideaki Nakajima; Takaharu Takamura; Alexander Bangirana; Hiroshi Itoh; Hisatoshi Baba
Journal:  J Neurosurg Spine       Date:  2007-08

Review 10.  ANCA-Associated Systemic Vasculitis Presenting With Hypertrophic Spinal Pachymeningitis: A Report of 2 Cases and Review of Literature.

Authors:  Xia Li; Jiuliang Zhao; Qian Wang; Yunyun Fei; Yan Zhao
Journal:  Medicine (Baltimore)       Date:  2015-11       Impact factor: 1.817

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