| Literature DB >> 28362444 |
Lucia Barbera1, Domenico Franco, Laura M De Plano, Giuseppe Gattuso, Salvatore P P Guglielmino, Germana Lentini, Nadia Manganaro, Nino Marino, Sebastiano Pappalardo, Melchiorre F Parisi, Fausto Puntoriero, Ilenia Pisagatti, Anna Notti.
Abstract
The remarkable affinity of deca-carboxylatopillar[5]arene WP5 towards the aminoglycoside antibiotic, amikacin, in aqueous media is reported; in vitro studies on Gram-positive bacteria (Staphylococcus aureus) show that drug entrapment inside WP5 also takes place in the presence of the microrganisms, thus pointing to WP5 as an appealing carrier for amikacin targeted delivery.Entities:
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Year: 2017 PMID： 28362444 DOI： 10.1039/c7ob00530j
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876