Adriana Costa Bacelo1, Pedro Emmanuel Alvarenga Americano do Brasil2, Cláudia Dos Santos Cople-Rodrigues3, Georg Ingebourg4, Eliane Paiva5, Andrea Ramalho6, Valeria Cavalcanti Rolla7. 1. Nutrition Service, National Institute of Infectious Diseases Evandro Chagas, Oswaldo Cruz Foundation, Av. Brasil 4365, Rio de Janeiro, RJ, 21040-900, Brazil. Electronic address: adriana.bacelo@ini.fiocruz.br. 2. Clinical Research Laboratory on Chagas Disease, National Institute of Infectious Diseases Evandro Chagas, Oswaldo Cruz Foundation, Av. Brasil 4365, Rio de Janeiro, RJ, 21040-900, Brazil. Electronic address: pedro.brasil@ini.fiocruz.br. 3. Nutrition Institute, Rio de Janeiro State University, Rua São Francisco Xavier 524, 12º Floor, Rio de Janeiro, RJ, 20550-900, Brazil. Electronic address: claudiacople@gmail.com. 4. Diagnostics Activities Coordination, Immunodiagnostic Section, National Institute of Infectious Diseases Evandro Chagas, Oswaldo Cruz Foundation, Av. Brasil 4365, Rio de Janeiro, RJ, 21040-900, Brazil. Electronic address: ingebourg.georg@ini.fiocruz.br. 5. Department of Nutrition, Augusto Motta University Center, Av. Paris 72, Rio de Janeiro, RJ, 21041-020, Brazil. Electronic address: elianepaivanutricao@gmail.com. 6. Josué de Castro Institute, Rio de Janeiro's Federal University, Av. Carlos Chagas Filho, 373, CCS Block J, 2º Floor, Rio de Janeiro, RJ, 21941-901, Brazil. Electronic address: aramalho.rj@gmail.com. 7. Clinical Research Laboratory on Mycobacteria, National Institute of Infectious Diseases Evandro Chagas, Oswaldo Cruz Foundation, Av. Brasil 4365, Rio de Janeiro, RJ, 21040-900, Brazil. Electronic address: valeria.rolla@ini.fiocruz.br.
Abstract
BACKGROUND: The World Health Organization (WHO) recommends the use of dietary counseling to overcome malnutrition for patients with tuberculosis, with or without HIV, however the response to nutritional treatment depends on patient's adherence to nutritional counseling. OBJECTIVE: Identify the degree of adherence to dietary counseling and predictors of adherence among patients undergoing tuberculosis treatment. DESIGN: Observational prospective follow-up study conducted in adults treating for tuberculosis with or without HIV. Self-reported adherence and 24-h diet recall were checked. Diet counseling according to WHO strategy was offered at each visit for all patients. The endpoint was the adherence to the recommended dietary allowance (RDA) and total calories consumed during tuberculosis treatment. Data were mainly analyzed with marginal models to estimate adjusted trajectories. RESULTS: Sixty-eight patients were included in the study. The maximum probability of total calories consumption of at least one RDA was 80%. The adherence to dietary counseling was low regardless of HIV infection. The negative determinants of adherence were the presence of loss of appetite and nausea/vomiting. For patients with loss of appetite and nausea/vomiting, the probability of total calories consumption of at least one RDA is less than 20% at any time. CONCLUSION: The loss of appetite and nausea/vomiting are highly prevalents and were the main causes of non-adherence to dietary counseling.
BACKGROUND: The World Health Organization (WHO) recommends the use of dietary counseling to overcome malnutrition for patients with tuberculosis, with or without HIV, however the response to nutritional treatment depends on patient's adherence to nutritional counseling. OBJECTIVE: Identify the degree of adherence to dietary counseling and predictors of adherence among patients undergoing tuberculosis treatment. DESIGN: Observational prospective follow-up study conducted in adults treating for tuberculosis with or without HIV. Self-reported adherence and 24-h diet recall were checked. Diet counseling according to WHO strategy was offered at each visit for all patients. The endpoint was the adherence to the recommended dietary allowance (RDA) and total calories consumed during tuberculosis treatment. Data were mainly analyzed with marginal models to estimate adjusted trajectories. RESULTS: Sixty-eight patients were included in the study. The maximum probability of total calories consumption of at least one RDA was 80%. The adherence to dietary counseling was low regardless of HIV infection. The negative determinants of adherence were the presence of loss of appetite and nausea/vomiting. For patients with loss of appetite and nausea/vomiting, the probability of total calories consumption of at least one RDA is less than 20% at any time. CONCLUSION: The loss of appetite and nausea/vomiting are highly prevalents and were the main causes of non-adherence to dietary counseling.
Authors: Prem Perumal; Mohamed Bilal Abdullatif; Harriet N Garlant; Isobella Honeyborne; Marc Lipman; Timothy D McHugh; Jo Southern; Ronan Breen; George Santis; Kalaiarasan Ellappan; Saka Vinod Kumar; Harish Belgode; Ibrahim Abubakar; Sanjeev Sinha; Seshadri S Vasan; Noyal Joseph; Karen E Kempsell Journal: Front Immunol Date: 2021-03-16 Impact factor: 7.561
Authors: Karim Damji; Ahmar H Hashmi; Lin Lin Kyi; Michele Vincenti-Delmas; Win Pa Pa Htun; Htet Ko Ko Aung; Tobias Brummaier; Chaisiri Angkurawaranon; Verena Carrara; Francois Nosten Journal: BMJ Open Date: 2022-01-07 Impact factor: 2.692