Akira Honda1, Yoichi Iizuka2, Junko Hirato3, Hiroki Kiyohara4, Haku Iizuka1. 1. Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan. 2. Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan. yoiizuka@gunma-u.ac.jp. 3. Department of Pathology, Gunma University Hospital, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan. 4. Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22, Showa, Maebashi, Gunma, 371-8511, Japan.
Abstract
INTRODUCTION: We report a rare case with multiple intradural-extramedullary spinal ependymomas with different histological features. CASE REPORT: A 26-year-old female presented to our hospital because of difficulty in walking due to progressive paresis. Magnetic resonance imaging of the thoracic spinal cord showed multiple spinal cord tumors. Surgical resection of these tumors was performed and a different histological diagnosis including World Health Organization Grade III anaplastic ependymoma and Grade II ependymoma was obtained using the resected specimen. Additional radiotherapy and chemotherapy were also performed, and a successful outcome has been maintained for at least 3 years after surgery. CONCLUSION: Surgical resections and subsequent radiotherapy and chemotherapy for cases with multiple intradural-extramedullary ependymomas can result in a good postoperative course.
INTRODUCTION: We report a rare case with multiple intradural-extramedullary spinal ependymomas with different histological features. CASE REPORT: A 26-year-old female presented to our hospital because of difficulty in walking due to progressive paresis. Magnetic resonance imaging of the thoracic spinal cord showed multiple spinal cord tumors. Surgical resection of these tumors was performed and a different histological diagnosis including World Health Organization Grade III anaplastic ependymoma and Grade II ependymoma was obtained using the resected specimen. Additional radiotherapy and chemotherapy were also performed, and a successful outcome has been maintained for at least 3 years after surgery. CONCLUSION: Surgical resections and subsequent radiotherapy and chemotherapy for cases with multiple intradural-extramedullary ependymomas can result in a good postoperative course.
Entities:
Keywords:
Ependymoma; Mixture of different histology; Multiple spinal cord tumor
Authors: Santiago Gil Robles; Cristobal Saldaña; Gregorio R Boto; Armando Martinez; Alvaro Perez Zamarron; Manuela Jorquera; Pedro Mata Journal: Spine (Phila Pa 1976) Date: 2005-05-01 Impact factor: 3.468
Authors: I J Pomeraniec; R F Dallapiazza; H M Sumner; M B Lopes; C I Shaffrey; J S Smith Journal: J Clin Neurosci Date: 2015-10-23 Impact factor: 1.961
Authors: Lisa B E Shields; David A Sun; Hilary A Highfield; Renato V LaRocca; Aaron C Spalding; Kaylyn D Sinicrope; Yi Ping Zhang; Christopher B Shields Journal: J Neurosurg Case Lessons Date: 2022-05-30