Literature DB >> 2836091

The onset of senescence is affected by DNA rearrangements of a discontinuous mitochondrial gene in Podospora anserina.

U Kück1, H D Osiewacz, U Schmidt, B Kappelhoff, E Schulte, U Stahl, K Esser.   

Abstract

Mapping and transcription studies have revealed that in Podospora anserina the causative agent of senescence, a mitochondrial plasmid (plDNA), is identical with intron 1 of the discontinuous gene for cytochrome-c-oxidase subunit 1 (COI), which is 2 kpb from the discontinuous gene for cytochrome b (Cytb). A mitochondrial mutant (ex1) devoid of the COI, but not of the Cytb gene provides longevity. A molecular model for the onset of senescence is presented.

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Year:  1985        PMID： 2836091     DOI： 10.1007/BF00421608

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  43 in total

1.  [Impossibility of obtaining uninterrupted and unlimited multiplication of the ascomycete Podospora anserina].

Authors:  G RIZET
Journal:  C R Hebd Seances Acad Sci       Date:  1953-10-12

2.  Genes inhibiting senescence in the ascomycete Podospora anserina.

Authors:  K Esser; W Keller
Journal:  Mol Gen Genet       Date:  1976-02-27

3.  Plasmid-like DNA is part of mitochondrial DNA in Podospora anserina.

Authors:  U Kück; U Stahl; K Esser
Journal:  Curr Genet       Date:  1981-05       Impact factor: 3.886

4.  Ethidium bromide rejuvenation of senescent cultures of Podospora anserina : Loss of senescence-specific DNA and recovery of normal mitochondrial DNA.

Authors:  F Koll; O Begel; A M Keller; C Vierny; L Belcour
Journal:  Curr Genet       Date:  1984-02       Impact factor: 3.886

5.  Inhibitors of mitochondrial function prevent senescence in the ascomycete Podosprora anserina.

Authors:  P Tudzynski; K Esser
Journal:  Mol Gen Genet       Date:  1977-05-20

6.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

7.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

8.  Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

Authors:  G K McMaster; G G Carmichael
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

9.  Replication and expression of a bacterial--mitochondrial hybrid plasmid in the fungus Podospora anserina.

Authors:  U Stahl; P Tudzynski; U Kück; K Esser
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

10.  Integration of mitochondrial gene sequences within the nuclear genome during senescence in a fungus.

Authors:  R M Wright; D J Cummings
Journal:  Nature       Date:  1983-03-03       Impact factor: 49.962
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  35 in total

1.  DNA sequence analysis of the 24.5 kilobase pair cytochrome oxidase subunit I mitochondrial gene from Podospora anserina: a gene with sixteen introns.

Authors:  D J Cummings; F Michel; K L McNally
Journal:  Curr Genet       Date:  1989-12       Impact factor: 3.886

2.  Integrative transformation of the ascomycete Podospora anserina: identification of the mating-type locus on chromosome VII of electrophoretically separated chromosomes.

Authors:  H D Osiewacz; A Skaletz; K Esser
Journal:  Appl Microbiol Biotechnol       Date:  1991-04       Impact factor: 4.813

3.  Construction of insertion mutants of Synechocystis sp. PCC 6803: evidence for an essential function of subunit IV of the cytochrome b6/f complex.

Authors:  H D Osiewacz
Journal:  Arch Microbiol       Date:  1992       Impact factor: 2.552

4.  Suppression of cytoplasmic senescence in Neurospora.

Authors:  A J Griffiths; Y Xiao; R Barton; C Myers
Journal:  Curr Genet       Date:  1992-05       Impact factor: 3.886

5.  GRISEA, a putative copper-activated transcription factor from Podospora anserina involved in differentiation and senescence.

Authors:  H D Osiewacz; U Nuber
Journal:  Mol Gen Genet       Date:  1996-08-27

6.  In organello replication and viral affinity of linear, extrachromosomal DNA of the ascomycete Ascobolus immersus.

Authors:  F Kempken; F Meinhardt; K Esser
Journal:  Mol Gen Genet       Date:  1989-09

7.  The intron of a plastid gene from a green alga contains an open reading frame for a reverse transcriptase-like enzyme.

Authors:  U Kück
Journal:  Mol Gen Genet       Date:  1989-08

Review 8.  Genetic conservation versus variability in mitochondria: the architecture of the mitochondrial genome in the petite-negative yeast Schizosaccharomyces pombe.

Authors:  Bernd Schäfer
Journal:  Curr Genet       Date:  2003-05-09       Impact factor: 3.886

9.  Evidence for a life span-prolonging effect of a linear plasmid in a longevity mutant of Podospora anserina.

Authors:  J Hermanns; A Asseburg; H D Osiewacz
Journal:  Mol Gen Genet       Date:  1994-05-10

10.  Three mitochondrial unassigned open reading frames of Podospora anserina represent remnants of a viral-type RNA polymerase gene.

Authors:  J Hermanns; H D Osiewacz
Journal:  Curr Genet       Date:  1994-02       Impact factor: 3.886
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