BACKGROUND: To compare the short and mid-term results of intraarticular triamcinolone hexacetonide and hyaluronic acid (HA) in knee osteoarthritis. METHODS: A prospective randomized study including 40 patients in steroid and 42 patients in HA group. The outcome was evaluated with Knee Society Score (KSS) and Visual Analog Scale (VAS). RESULT: On KSS function and VAS score, there was no difference till four weeks. On KSS pain there was no difference till 12 weeks (P > 0.05) after that score of steroid group deteriorated rapidly. At six months HA was significantly better than a steroid. CONCLUSION: The HA seems to be better for pain relief and functionality in the short and mid-term periods.
RCT Entities:
BACKGROUND: To compare the short and mid-term results of intraarticular triamcinolone hexacetonide and hyaluronic acid (HA) in knee osteoarthritis. METHODS: A prospective randomized study including 40 patients in steroid and 42 patients in HA group. The outcome was evaluated with Knee Society Score (KSS) and Visual Analog Scale (VAS). RESULT: On KSS function and VAS score, there was no difference till four weeks. On KSS pain there was no difference till 12 weeks (P > 0.05) after that score of steroid group deteriorated rapidly. At six months HA was significantly better than a steroid. CONCLUSION: The HA seems to be better for pain relief and functionality in the short and mid-term periods.
Entities:
Keywords:
Hyaluronic acid; Intra-articular; Knee Society Score; Osteoarthritis; Steroid
Authors: W Zhang; G Nuki; R W Moskowitz; S Abramson; R D Altman; N K Arden; S Bierma-Zeinstra; K D Brandt; P Croft; M Doherty; M Dougados; M Hochberg; D J Hunter; K Kwoh; L S Lohmander; P Tugwell Journal: Osteoarthritis Cartilage Date: 2010-02-11 Impact factor: 6.576
Authors: Benton E Heyworth; Jonathan H Lee; Paul D Kim; Carter B Lipton; Robert J Strauch; Melvin P Rosenwasser Journal: J Hand Surg Am Date: 2008-01 Impact factor: 2.230