Literature DB >> 28360089

ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis.

Klaus Ley1, Norbert Gerdes2, Holger Winkels2.   

Abstract

OBJECTIVE: Immune cells play a critical role in atherosclerosis. Costimulatory and coinhibitory molecules of the tumor necrosis factor receptor and CD28 immunoglobulin superfamilies not only shape T-cell and B-cell responses but also have a major effect on antigen-presenting cells and nonimmune cells. APPROACH AND
RESULTS: Pharmacological inhibition or activation of costimulatory and coinhibitory molecules and genetic deletion demonstrated their involvement in atherosclerosis. This review highlights recent advances in understanding how costimulatory and coinhibitory pathways shape the immune response in atherosclerosis.
CONCLUSIONS: Insights gained from costimulatory and coinhibitory molecule function in atherosclerosis may inform future therapeutic approaches.
© 2017 American Heart Association, Inc.

Entities:  

Keywords:  B-lymphocytes; antigen-presenting cells; atherosclerosis; immunoglobulins; receptors, tumor necrosis factor

Mesh：

Substances：

Year:  2017        PMID： 28360089      PMCID： PMC5424816          DOI： 10.1161/ATVBAHA.117.308611

Source DB:  PubMed          Journal:  Arterioscler Thromb Vasc Biol        ISSN： 1079-5642            Impact factor:   8.311


  211 in total

Review 1.  CD27 and CD70 in T cell and B cell activation.

Authors:  Jannie Borst; Jenny Hendriks; Yanling Xiao
Journal:  Curr Opin Immunol       Date:  2005-06       Impact factor: 7.486

2.  CD30/TNF receptor-associated factor interaction: NF-kappa B activation and binding specificity.

Authors:  S Y Lee; S Y Lee; G Kandala; M L Liou; H C Liou; Y Choi
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-03       Impact factor: 11.205

3.  Regulatory T-Cell Plasticity: Another Layer of Complexity in Atherosclerosis.

Authors:  Hafid Ait-Oufella; Alain Tedgui
Journal:  Circ Res       Date:  2016-05-13       Impact factor: 17.367

4.  Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques.

Authors:  Won-Jung Kim; Eun-Mi Bae; Yoon-Joong Kang; Hyung-Uk Bae; Su Hyung Hong; Joo Y Lee; Jeong-Euy Park; Byoung S Kwon; Kyoungho Suk; Won-Ha Lee
Journal:  Immunology       Date:  2006-11       Impact factor: 7.397

Review 5.  Immune regulation by CD40 and its ligand GP39.

Authors:  T M Foy; A Aruffo; J Bajorath; J E Buhlmann; R J Noelle
Journal:  Annu Rev Immunol       Date:  1996       Impact factor: 28.527

6.  CD27 deficiency is associated with combined immunodeficiency and persistent symptomatic EBV viremia.

Authors:  Joris M van Montfrans; Andy I M Hoepelman; Sigrid Otto; Marielle van Gijn; Lisette van de Corput; Roel A de Weger; Linda Monaco-Shawver; Pinaki P Banerjee; Elisabeth A M Sanders; Cornelia M Jol-van der Zijde; Michael R Betts; Jordan S Orange; Andries C Bloem; Kiki Tesselaar
Journal:  J Allergy Clin Immunol       Date:  2011-12-24       Impact factor: 10.793

7.  CD137-inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice.

Authors:  In-Hyuk Jung; Jae-Hoon Choi; Jing Jin; Se-Jin Jeong; Sejin Jeon; Chaeji Lim; Mi-Ran Lee; Ji-Young Yoo; Seong-Keun Sonn; Young Ho Kim; Beom Kyu Choi; Byoung S Kwon; Ju-Young Seoh; Cheol Whan Lee; Dae-Yong Kim; Goo Taeg Oh
Journal:  FASEB J       Date:  2014-07-24       Impact factor: 5.191

8.  CCR5+T-bet+FoxP3+ Effector CD4 T Cells Drive Atherosclerosis.

Authors:  Jie Li; Sara McArdle; Amin Gholami; Takayuki Kimura; Dennis Wolf; Teresa Gerhardt; Jacqueline Miller; Christian Weber; Klaus Ley
Journal:  Circ Res       Date:  2016-03-28       Impact factor: 17.367

9.  Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent.

Authors:  Elena Galkina; Alexandra Kadl; John Sanders; Danielle Varughese; Ian J Sarembock; Klaus Ley
Journal:  J Exp Med       Date:  2006-05-08       Impact factor: 14.307

10.  CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants.

Authors:  J Trebing; M El-Mesery; V Schäfer; D Weisenberger; D Siegmund; K Silence; H Wajant
Journal:  Cell Death Dis       Date:  2014-01-30       Impact factor: 8.469
View more
  15 in total

1.  Updates on Approaches for Studying Atherosclerosis.

Authors:  Congqing Wu; Alan Daugherty; Hong S Lu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-04       Impact factor: 8.311

2.  Pig and Mouse Models of Hyperlipidemia and Atherosclerosis.

Authors:  Godfrey S Getz; Catherine A Reardon
Journal:  Methods Mol Biol       Date:  2022

Review 3.  How the immune system shapes atherosclerosis: roles of innate and adaptive immunity.

Authors:  Payel Roy; Marco Orecchioni; Klaus Ley
Journal:  Nat Rev Immunol       Date:  2021-08-13       Impact factor: 108.555

Review 4.  Adaptive immunity: an emerging player in the progression of NAFLD.

Authors:  Salvatore Sutti; Emanuele Albano
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2019-10-11       Impact factor: 46.802

Review 5.  Renin-Angiotensin System and Cardiovascular Functions.

Authors:  Chia-Hua Wu; Shayan Mohammadmoradi; Jeff Z Chen; Hisashi Sawada; Alan Daugherty; Hong S Lu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2018-07       Impact factor: 8.311

6.  T Cells in Atherosclerosis in Ldlr-/- and Apoe-/- Mice.

Authors:  Godfrey S Getz; Catherine A Reardon
Journal:  J Immunol Sci       Date:  2018-06-27

7.  CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice.

Authors:  Hilman Zulkifli Amin; Naoto Sasaki; Tomoya Yamashita; Taiji Mizoguchi; Tomohiro Hayashi; Takuo Emoto; Takuya Matsumoto; Naofumi Yoshida; Tokiko Tabata; Sayo Horibe; Shoji Kawauchi; Yoshiyuki Rikitake; Ken-Ichi Hirata
Journal:  Sci Rep       Date:  2019-05-30       Impact factor: 4.379

Review 8.  Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS-) vs. Alternatively Activated Macrophages.

Authors:  Marco Orecchioni; Yanal Ghosheh; Akula Bala Pramod; Klaus Ley
Journal:  Front Immunol       Date:  2019-05-24       Impact factor: 7.561

9.  Correlations of the expression of γδ T cells and their co-stimulatory molecules TIGIT, PD-1, ICOS and BTLA with PR and PIBF in the peripheral blood and decidual tissues of women with unexplained recurrent spontaneous abortion.

Authors:  Q Liang; L Tong; L Xiang; S Shen; C Pan; C Liu; H Zhang
Journal:  Clin Exp Immunol       Date:  2020-10-28       Impact factor: 4.330

10.  Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease.

Authors:  Michael Lacy; Christina Bürger; Annelie Shami; Maiwand Ahmadsei; Holger Winkels; Katrin Nitz; Claudia M van Tiel; Tom T P Seijkens; Pascal J H Kusters; Ela Karshovka; Koen H M Prange; Yuting Wu; Sanne L N Brouns; Sigrid Unterlugauer; Marijke J E Kuijpers; Myrthe E Reiche; Sabine Steffens; Andreas Edsfeldt; Remco T A Megens; Johan W M Heemskerk; Isabel Goncalves; Christian Weber; Norbert Gerdes; Dorothee Atzler; Esther Lutgens
Journal:  Nat Commun       Date:  2021-06-18       Impact factor: 14.919
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.