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Literature DB >> 2835770

Interaction of a common cellular transcription factor, ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters.

Abstract

We have previously identified a cellular transcription factor, ATF, which is involved in the expression of multiple adenovirus E1a-inducible genes. Here we show that ATF also binds to regulatory elements in cellular cAMP-inducible promoters. In these cellular promoters, ATF binds to a consensus sequence that has been previously shown to be necessary and in some instances sufficient for cAMP-inducible transcription. Furthermore, we show that binding of ATF to these promoter elements is required for the constitutive in vitro transcriptional activity of the cAMP-inducible somatostatin gene. Taken together, our results suggest that a common cellular transcription factor, ATF, can be regulated in vivo by two apparently unrelated inducing agents: the adenovirus E1a protein and cAMP.

Entities: Chemical Gene

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Year: 1988 PMID： 2835770 PMCID： PMC280216 DOI： 10.1073/pnas.85.10.3396

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

17 in total

1. Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains.

Authors: J M Short; A Wynshaw-Boris; H P Short; R W Hanson
Journal: J Biol Chem Date: 1986-07-25 Impact factor: 5.157

Review 2. Adenovirus promoters and E1A transactivation.

Authors: A J Berk
Journal: Annu Rev Genet Date: 1986 Impact factor: 16.830

3. An adenovirus E1a protein region required for transformation and transcriptional repression.

Authors: J W Lillie; M Green; M R Green
Journal: Cell Date: 1986-09-26 Impact factor: 41.582

4. A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor.

Authors: L A Chodosh; R W Carthew; P A Sharp
Journal: Mol Cell Biol Date: 1986-12 Impact factor: 4.272

5. Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

Authors: T Tsukada; J S Fink; G Mandel; R H Goodman
Journal: J Biol Chem Date: 1987-06-25 Impact factor: 5.157

6. Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene.

Authors: M R Montminy; L M Bilezikjian
Journal: Nature Date: 1987 Jul 9-15 Impact factor: 49.962

7. Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP.

Authors: E J Lewis; C A Harrington; D M Chikaraishi
Journal: Proc Natl Acad Sci U S A Date: 1987-06 Impact factor: 11.205

8. Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

Authors: M R Montminy; K A Sevarino; J A Wagner; G Mandel; R H Goodman
Journal: Proc Natl Acad Sci U S A Date: 1986-09 Impact factor: 11.205

9. Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

Authors: B J Silver; J A Bokar; J B Virgin; E A Vallen; A Milsted; J H Nilson
Journal: Proc Natl Acad Sci U S A Date: 1987-04 Impact factor: 11.205

10. A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro.

Authors: K A Lee; M R Green
Journal: EMBO J Date: 1987-05 Impact factor: 11.598

112 in total

Review 1. ATF3 and stress responses.

Authors: T Hai; C D Wolfgang; D K Marsee; A E Allen; U Sivaprasad
Journal: Gene Expr Date: 1999

2. Adenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1.

Authors: U Müller; T Kleinberger; T Shenk
Journal: J Virol Date: 1992-10 Impact factor: 5.103

3. Multiple ocs-like elements required for efficient transcription of the mannopine synthase gene of T-DNA in maize protoplasts.

Authors: P C Fox; V Vasil; I K Vasil; W B Gurley
Journal: Plant Mol Biol Date: 1992-10 Impact factor: 4.076

4. A DNA element that regulates expression of an endogenous retrovirus during F9 cell differentiation is E1A dependent.

Authors: B T Lamb; K Satyamoorthy; D Solter; A Basu; M Q Xu; R Weinmann; C C Howe
Journal: Mol Cell Biol Date: 1992-11 Impact factor: 4.272

5. CAAT/enhancer binding protein is able to bind to ATF/CRE elements.

Authors: O Bakker; M G Parker
Journal: Nucleic Acids Res Date: 1991-03-25 Impact factor: 16.971

6. Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants.

Authors: E Lam; P N Benfey; P M Gilmartin; R X Fang; N H Chua
Journal: Proc Natl Acad Sci U S A Date: 1989-10 Impact factor: 11.205

7. Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter.

Authors: L A Berkowitz; K T Riabowol; M Z Gilman
Journal: Mol Cell Biol Date: 1989-10 Impact factor: 4.272

8. Characterization of cellular factors that interact with the human T-cell leukemia virus type I p40x-responsive 21-base-pair sequence.

Authors: K T Jeang; I Boros; J Brady; M Radonovich; G Khoury
Journal: J Virol Date: 1988-12 Impact factor: 5.103

9. Distinguishable promoter elements are involved in transcriptional activation by E1a and cyclic AMP.

Authors: K A Lee; J S Fink; R H Goodman; M R Green
Journal: Mol Cell Biol Date: 1989-10 Impact factor: 4.272

10. Mechanism of cAMP regulation of renin gene transcription by proximal promoter.

Authors: K Tamura; S Umemura; S Yamaguchi; T Iwamoto; S Kobayashi; A Fukamizu; K Murakami; M Ishii
Journal: J Clin Invest Date: 1994-11 Impact factor: 14.808