Literature DB >> 28357683

Targeting Frailty in Heart Failure.

Susan M Joseph1, Michael W Rich2.   

Abstract

OPINION STATEMENT: Frailty is a systemic syndrome characterized by impaired physiologic reserve, slowness, weakness, and wasting. It is associated with, but distinct from, aging, disability, and multimorbidity. Frailty is extremely common in patients with heart failure and portends a worse prognosis. The two syndromes worsen one another via complex molecular and cellular mechanisms which are not fully understood but include increased levels of stress hormones and cytokines. In this article, we discuss the mechanisms of frailty and review common frailty metrics. We review and summarize the literature on the impact of frailty in heart failure and discuss treatment and management options.

Entities:  

Keywords:  Frailty; Fried criteria; Heart failure; Multimorbidity; Sarcopenia

Year:  2017        PMID： 28357683     DOI： 10.1007/s11936-017-0527-5

Source DB:  PubMed          Journal:  Curr Treat Options Cardiovasc Med        ISSN： 1092-8464


  44 in total

1.  The Fourth INTERMACS Annual Report: 4,000 implants and counting.

Authors:  James K Kirklin; David C Naftel; Robert L Kormos; Lynne W Stevenson; Francis D Pagani; Marissa A Miller; J Timothy Baldwin; James B Young
Journal:  J Heart Lung Transplant       Date:  2012-02       Impact factor: 10.247

2.  Frailty in older adults: evidence for a phenotype.

Authors:  L P Fried; C M Tangen; J Walston; A B Newman; C Hirsch; J Gottdiener; T Seeman; R Tracy; W J Kop; G Burke; M A McBurnie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-03       Impact factor: 6.053

3.  Frailty and outcomes after implantation of left ventricular assist device as destination therapy.

Authors:  Shannon M Dunlay; Soon J Park; Lyle D Joyce; Richard C Daly; John M Stulak; Sheila M McNallan; Véronique L Roger; Sudhir S Kushwaha
Journal:  J Heart Lung Transplant       Date:  2013-12-27       Impact factor: 10.247

4.  Frailty, core muscle size, and mortality in patients undergoing open abdominal aortic aneurysm repair.

Authors:  Jay Soong-Jin Lee; Kevin He; Calista M Harbaugh; Douglas E Schaubel; Christopher J Sonnenday; Stewart C Wang; Michael J Englesbe; Jonathan L Eliason
Journal:  J Vasc Surg       Date:  2011-01-07       Impact factor: 4.268

Review 5.  Testosterone supplementation in heart failure: a meta-analysis.

Authors:  Mustafa Toma; Finlay A McAlister; Erin E Coglianese; Venkatesan Vidi; Samip Vasaiwala; Jeffrey A Bakal; Paul W Armstrong; Justin A Ezekowitz
Journal:  Circ Heart Fail       Date:  2012-04-17       Impact factor: 8.790

Review 6.  Protein and energy supplementation in elderly people at risk from malnutrition.

Authors:  Anne C Milne; Jan Potter; Angela Vivanti; Alison Avenell
Journal:  Cochrane Database Syst Rev       Date:  2009-04-15

7.  Frailty consensus: a call to action.

Authors:  John E Morley; Bruno Vellas; G Abellan van Kan; Stefan D Anker; Juergen M Bauer; Roberto Bernabei; Matteo Cesari; W C Chumlea; Wolfram Doehner; Jonathan Evans; Linda P Fried; Jack M Guralnik; Paul R Katz; Theodore K Malmstrom; Roger J McCarter; Luis M Gutierrez Robledo; Ken Rockwood; Stephan von Haehling; Maurits F Vandewoude; Jeremy Walston
Journal:  J Am Med Dir Assoc       Date:  2013-06       Impact factor: 4.669

Review 8.  The wasting continuum in heart failure: from sarcopenia to cachexia.

Authors:  Stephan von Haehling
Journal:  Proc Nutr Soc       Date:  2015-08-12       Impact factor: 6.297

9.  Model for end-stage liver disease score predicts left ventricular assist device operative transfusion requirements, morbidity, and mortality.

Authors:  Jennifer C Matthews; Francis D Pagani; Jonathan W Haft; Todd M Koelling; David C Naftel; Keith D Aaronson
Journal:  Circulation       Date:  2010-01-04       Impact factor: 29.690

Review 10.  Cardiac cachexia: hic et nunc.

Authors:  Goran Loncar; Jochen Springer; Markus Anker; Wolfram Doehner; Mitja Lainscak
Journal:  J Cachexia Sarcopenia Muscle       Date:  2016-07-01       Impact factor: 12.910
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  13 in total

1.  Report from the American Society of Transplantation on frailty in solid organ transplantation.

Authors:  Jon Kobashigawa; Darshana Dadhania; Sangeeta Bhorade; Deborah Adey; Joseph Berger; Geetha Bhat; Marie Budev; Andres Duarte-Rojo; Michael Dunn; Shelley Hall; Meera N Harhay; Kirsten L Johansen; Susan Joseph; Cassie C Kennedy; Evan Kransdorf; Krista L Lentine; Raymond J Lynch; Mara McAdams-DeMarco; Shunji Nagai; Michael Olymbios; Jignesh Patel; Sean Pinney; Joanna Schaenman; Dorry L Segev; Palak Shah; Lianne G Singer; Jonathan P Singer; Christopher Sonnenday; Puneeta Tandon; Elliot Tapper; Stefan G Tullius; Michael Wilson; Martin Zamora; Jennifer C Lai
Journal:  Am J Transplant       Date:  2018-12-22       Impact factor: 8.086

Review 2.  Frailty Is Intertwined With Heart Failure: Mechanisms, Prevalence, Prognosis, Assessment, and Management.

Authors:  Ambarish Pandey; Dalane Kitzman; Gordon Reeves
Journal:  JACC Heart Fail       Date:  2019-12       Impact factor: 12.035

3.  A Simple Effective Method for Frailty in Heart Failure with Impact on Clinical Outcomes in North Indian Population.

Authors:  Gurbhej Singh; Rohit Tandon; Neelesh C Pandey; Namita Bansal; Abhishek Goyal; Bhupinder Singh; Shibba Takkar Chhabra; Naved Aslam; Gurpreet Singh Wander; Bishav Mohan
Journal:  J Saudi Heart Assoc       Date:  2021-08-02

Review 4.  Domain Management Approach to Heart Failure in the Geriatric Patient: Present and Future.

Authors:  Eiran Z Gorodeski; Parag Goyal; Scott L Hummel; Ashok Krishnaswami; Sarah J Goodlin; Linda L Hart; Daniel E Forman; Nanette K Wenger; James N Kirkpatrick; Karen P Alexander
Journal:  J Am Coll Cardiol       Date:  2018-05-01       Impact factor: 24.094

5.  The Crossroads of Frailty and Heart Failure: What More Can We Learn?

Authors:  Quin E Denfeld; Christopher S Lee
Journal:  J Card Fail       Date:  2018-10-06       Impact factor: 5.712

Review 6.  Frailty in Heart Failure: Implications for Management.

Authors:  Cristiana Vitale; Ilaria Spoletini; Giuseppe Mc Rosano
Journal:  Card Fail Rev       Date:  2018-08

7.  Background and Design of the Biological and Physiological Mechanisms of Symptom Clusters in Heart Failure (BIOMES-HF) Study.

Authors:  Quin E Denfeld; S Albert Camacho; Nathan Dieckmann; Shirin O Hiatt; Mary Roberts Davis; Daniela V Cramer; Allissah Rupert; Beth A Habecker; Christopher S Lee
Journal:  J Card Fail       Date:  2022-01-16       Impact factor: 6.592

Review 8.  Hypertension, heart failure, and frailty in older people: A common but unclear situation.

Authors:  Miguel Camafort; Kazuomi Kario
Journal:  J Clin Hypertens (Greenwich)       Date:  2020-08-20       Impact factor: 3.738

Review 9.  The aging transplant population and immunobiology: any therapeutic implication?

Authors:  Joanna Schaenman; Deena Goldwater
Journal:  Curr Opin Organ Transplant       Date:  2020-06       Impact factor: 2.269

10.  Low Docosahexaenoic Acid, Dihomo-Gamma-Linolenic Acid, and Arachidonic Acid Levels Associated with Long-Term Mortality in Patients with Acute Decompensated Heart Failure in Different Nutritional Statuses.

Authors:  Shohei Ouchi; Tetsuro Miyazaki; Kazunori Shimada; Yurina Sugita; Megumi Shimizu; Azusa Murata; Takao Kato; Tatsuro Aikawa; Shoko Suda; Tomoyuki Shiozawa; Masaru Hiki; Shuhei Takahashi; Hiroshi Iwata; Takatoshi Kasai; Katsumi Miyauchi; Hiroyuki Daida
Journal:  Nutrients       Date:  2017-08-30       Impact factor: 5.717
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