Literature DB >> 28357524

Molecular connections of obesity and aging: a focus on adipose protein 53 and retinoblastoma protein.

Dinh-Toi Chu1,2,3, Yang Tao4.   

Abstract

Obesity is an induced health problem that human beings have been facing with non-optimal treatment so far. Humans are on average getting fatter with age, and obesity and aging interact each other to shorten lifetime and decrease life quality. Obesity also causes several aging related-disorders such as cancer, strokes, cardiovascular disease, high blood pressure and type 2 diabetes. So, the molecular connections between aging and obesity are promising targets for bio-medical researches and innovative therapies of many health problems. In this review, we discuss the findings of adipose p53 and Rb-two central molecular linkages between aging and obesity-on lipid metabolism and obesity.

Entities:  

Keywords:  Aging and obesity; p53 and Rb on adipogenesis; p53 and Rb on obesity

Mesh：

Substances：

Year:  2017        PMID： 28357524     DOI： 10.1007/s10522-017-9698-4

Source DB:  PubMed          Journal:  Biogerontology        ISSN： 1389-5729            Impact factor:   4.277


  5 in total

1.  Childhood Obesity Is a High-risk Factor for Hypertriglyceridemia: A Case-control Study in Vietnam.

Authors:  Nguyen Thi Hong Hanh; Le Thi Tuyet; Duong Thi Anh Dao; Yang Tao; Dinh-Toi Chu
Journal:  Osong Public Health Res Perspect       Date:  2017-04-30

Review 2.  The p53/Adipose-Tissue/Cancer Nexus.

Authors:  Kevin Zwezdaryk; Deborah Sullivan; Zubaida Saifudeen
Journal:  Front Endocrinol (Lausanne)       Date:  2018-08-14       Impact factor: 5.555

3.  Time-restricted feeding improves adaptation to chronically alternating light-dark cycles.

Authors:  Maaike Schilperoort; Rosa van den Berg; Martijn E T Dollé; Conny T M van Oostrom; Karina Wagner; Lauren L Tambyrajah; Paul Wackers; Tom Deboer; Gerben Hulsegge; Karin I Proper; Harry van Steeg; Till Roenneberg; Nienke R Biermasz; Patrick C N Rensen; Sander Kooijman; Linda W M van Kerkhof
Journal:  Sci Rep       Date:  2019-05-27       Impact factor: 4.379

4.  Eating Behaviors in Relation to Child Weight Status and Maternal Education.

Authors:  Priscilla Ayine; Vaithinathan Selvaraju; Chandra M K Venkatapoorna; Yida Bao; Philippe Gaillard; Thangiah Geetha
Journal:  Children (Basel)       Date:  2021-01-07

5.  NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling.

Authors:  Feilin Liu; Jiahong Shi; Yingyao Zhang; Aobo Lian; Xing Han; Kuiyang Zuo; Mingsheng Liu; Tong Zheng; Fei Zou; Xiaomei Liu; Minghua Jin; Ying Mu; Gang Li; Guanfang Su; Jinyu Liu
Journal:  Oxid Med Cell Longev       Date:  2019-12-04       Impact factor: 6.543
  5 in total

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