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Literature DB >> 2835694

Stimulation of brain Na,K-ATPase by norepinephrine but not taurine.

Abstract

The effect of taurine on rat and hamster brain Na,K-ATPase was examined and compared to norepinephrine (NE) stimulation of the enzyme. Although NE stimulation of microsomal Na,K-ATPase was observed in the presence of the cell cytosolic fraction, taurine was without effect in the presence and absence of this fraction. Taurine also failed to modulate pubescent and mature hamster brain Na,K-ATPase. Presence or absence of ion chelators did not change taurine's effect. These results are discussed in relation to previous reports of taurine and catecholamine stimulation of Na,K-ATPase.

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Year: 1988 PMID： 2835694 DOI： 10.1007/BF00971858

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

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References

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Stimulation of brain Na,K-ATPase by norepinephrine but not taurine.

1. A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE.

2. Studies on the effect of catecholamines and chelating agents on the synaptic membrane Na+,K+-ATPase activity in the presence and absence of hydroxylamine.

3. Does Na,K-ATPase play a role in the regulation of neurotransmitter release by prejunctional alpha-adrenoceptors?

4. Effect of biogenic amines and GABA on ATPase activities in mouse tissue.

5. Receptor independent stimulatory effect of noradrenaline on Na,K-ATPase in rat brain homogenate. Role of lipid peroxidation.

6. Effects of adrenergic agonists and antagonists and of the catechol nucleus on the Na+, K+-ATPase and Mg2+-ATPase activities of synaptosomes.

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