Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Liver disease: Conscious uncoupling in NASH.

Literature DB >> 28356593

Liver disease: Conscious uncoupling in NASH.

M Teresa Villanueva.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2017 PMID： 28356593 DOI： 10.1038/nrd.2017.60

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

× No keyword cloud information.

1 in total

1. Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.

Authors: Pi-Xiao Wang; Yan-Xiao Ji; Xiao-Jing Zhang; Ling-Ping Zhao; Zhen-Zhen Yan; Peng Zhang; Li-Jun Shen; Xia Yang; Jing Fang; Song Tian; Xue-Yong Zhu; Jun Gong; Xin Zhang; Qiao-Fang Wei; Yong Wang; Jing Li; Lu Wan; Qingguo Xie; Zhi-Gang She; Zhihua Wang; Zan Huang; Hongliang Li
Journal: Nat Med Date: 2017-02-20 Impact factor: 53.440

1 in total

7 in total

1. The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis.

Authors: Peng Zhang; Pi-Xiao Wang; Ling-Ping Zhao; Xin Zhang; Yan-Xiao Ji; Xiao-Jing Zhang; Chun Fang; Yue-Xin Lu; Xia Yang; Mao-Mao Gao; Yan Zhang; Song Tian; Xue-Yong Zhu; Jun Gong; Xin-Liang Ma; Feng Li; Zhihua Wang; Zan Huang; Zhi-Gang She; Hongliang Li
Journal: Nat Med Date: 2017-12-11 Impact factor: 53.440

Review 2. Crystallographic mining of ASK1 regulators to unravel the intricate PPI interfaces for the discovery of small molecule.

Authors: Ashish Kumar Agrahari; Madhu Dikshit; Shailendra Asthana
Journal: Comput Struct Biotechnol J Date: 2022-07-11 Impact factor: 6.155

3. Breviscapine alleviates NASH by inhibiting TGF-β-activated kinase 1-dependent signaling.

Authors: Tian Lan; Shuo Jiang; Jing Zhang; Qiqing Weng; Yang Yu; Haonan Li; Song Tian; Xin Ding; Sha Hu; Yiqi Yang; Weixuan Wang; Lexun Wang; Duosheng Luo; Xue Xiao; Shenghua Piao; Qing Zhu; Xianglu Rong; Jiao Guo
Journal: Hepatology Date: 2021-12-19 Impact factor: 17.298

Liver disease: Conscious uncoupling in NASH.

1. Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.

1. The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis.

Review 2. Crystallographic mining of ASK1 regulators to unravel the intricate PPI interfaces for the discovery of small molecule.

3. Breviscapine alleviates NASH by inhibiting TGF-β-activated kinase 1-dependent signaling.

4. Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression.

5. Hepatocyte phosphatase DUSP22 mitigates NASH-HCC progression by targeting FAK.

6. Interleukin-22 drives a metabolic adaptive reprogramming to maintain mitochondrial fitness and treat liver injury.

7. Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress.