Literature DB >> 28353527

Baclofen Pumps: Uses and Complications.

Seth M Woolf1, Carl R Baum.   

Abstract

Intrathecal baclofen therapy, given via an implanted pump in the abdominal wall either as a continuous infusion or bolus dosing, has been used for more than 25 years to treat the spasticity and dystonia associated with various brain and spinal cord conditions. Pediatric clinicians occasionally encounter baclofen pumps, and in the pediatric setting, significant morbidity can arise from their use. This article presents the background, mechanism of action, uses, and complications of intrathecal baclofen therapy and discusses various management strategies should complications occur.

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Year:  2017        PMID: 28353527     DOI: 10.1097/PEC.0000000000001090

Source DB:  PubMed          Journal:  Pediatr Emerg Care        ISSN: 0749-5161            Impact factor:   1.454


  4 in total

1.  Intrathecal baclofen therapy for treatment of spasticity in infants and small children under 6 years of age.

Authors:  Christian Hagemann; Ilka Schmitt; Grischa Lischetzki; Philip Kunkel
Journal:  Childs Nerv Syst       Date:  2019-08-09       Impact factor: 1.475

2.  Unusual mechanical failures of intrathecal baclofen pump systems: symptoms, signs, and trouble shooting.

Authors:  Janina Gburek-Augustat; Matthias Krause; Matthias Bernhard; Ina Sorge; Daniel Gräfe; Manuela Siekmeyer; Ulf Nestler; Andreas Merkenschlager
Journal:  Childs Nerv Syst       Date:  2021-04-08       Impact factor: 1.475

3.  Novel Opipramol-Baclofen Combination Alleviates Depression and Craving and Facilitates Recovery From Substance Use Disorder-An Animal Model and a Human Study.

Authors:  Tzofnat Bareli; Hadas Levi Ahdoot; Hilla Ben Moshe; Royi Barnea; Gal Warhaftig; Iris Gispan; Rachel Maayan; Paola Rosca; Abraham Weizman; Gal Yadid
Journal:  Front Behav Neurosci       Date:  2021-12-23       Impact factor: 3.558

4.  Critical clinical situations in adult patients with Mucopolysaccharidoses (MPS).

Authors:  Karolina M Stepien; Anait K Gevorkyan; Christian J Hendriksz; Tinatin V Lobzhanidze; Jordi Pérez-López; Govind Tol; Mireia Del Toro Riera; Nato D Vashakmadze; Christina Lampe
Journal:  Orphanet J Rare Dis       Date:  2020-05-14       Impact factor: 4.123

  4 in total

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