Literature DB >> 28353346

Csp-Csp3 Bond Formation via Iron(III)-Promoted Hydroalkynylation of Unactivated Alkenes.

Yangyong Shen1, Bo Huang1, Jing Zheng1, Chen Lin1, Yu Liu2, Sunliang Cui1.   

Abstract

An iron(III)-promoted hydroalkynylation of unactivated alkenes toward Csp-Csp3 bond formation has been developed. Various alkenes, including mono-, di-, and trisubstituted alkenes, could all smoothly convert to structural diversified alkynes in this chemoselective protocol. Additionally, the scalability was unraveled and the further divergent transformations of products were conducted to demonstrate the synthetic utility.

Entities:  

Year:  2017        PMID: 28353346     DOI: 10.1021/acs.orglett.7b00499

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Metal-free visible light photoredox enables generation of carbyne equivalents via phosphonium ylide C-H activation.

Authors:  Mrinmoy Das; Minh Duy Vu; Qi Zhang; Xue-Wei Liu
Journal:  Chem Sci       Date:  2018-12-04       Impact factor: 9.825

Review 2.  Alkynylation of radicals: spotlight on the "Third Way" to transfer triple bonds.

Authors:  Franck Le Vaillant; Jérôme Waser
Journal:  Chem Sci       Date:  2019-08-13       Impact factor: 9.825

3.  Visible Light-Enabled sp3 -C-H Functionalization with Chloro- and Bromoalkynes: Chemoselective Route to Vinylchlorides or Alkynes.

Authors:  Tapas Adak; Marvin Hoffmann; Sina Witzel; Matthias Rudolph; Andreas Dreuw; A Stephen K Hashmi
Journal:  Chemistry       Date:  2020-10-15       Impact factor: 5.236

4.  Reactions of diborenes with terminal alkynes: mechanisms of ligand-controlled anti-selective hydroalkynylation, cycloaddition and C[triple bond, length as m-dash]C triple bond scission.

Authors:  Lukas Englert; Uwe Schmidt; Michael Dömling; Max Passargus; Tom E Stennett; Alexander Hermann; Merle Arrowsmith; Marcel Härterich; Jonas Müssig; Alexandra Phillipps; Dominic Prieschl; Anna Rempel; Felix Rohm; Krzysztof Radacki; Fabian Schorr; Torsten Thiess; J Oscar C Jiménez-Halla; Holger Braunschweig
Journal:  Chem Sci       Date:  2021-06-21       Impact factor: 9.825

  4 in total

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