Literature DB >> 28353215

Severe Asthma in Children.

Bradley E Chipps1, Neil G Parikh2, Sheena K Maharaj2.   

Abstract

PURPOSE OF REVIEW: The aim of this study is to characterize, diagnose, evaluate, and treat severe childhood asthma. RECENT
FINDINGS: Understanding the occurrence of the physiologic and clinical presentations of childhood severe asthma, the treatment and response may be predicted by biomarkers, but the patient's response is highly variable. The onset of severe asthma occurs early and is primarily predicted by severity of viral infection and coexistence of the atopic state.

Entities:  

Keywords:  Biologic therapy; Biomarkers; Childhood asthma; Pharmacologic therapy; Severe asthma

Mesh:

Substances:

Year:  2017        PMID: 28353215     DOI: 10.1007/s11882-017-0688-z

Source DB:  PubMed          Journal:  Curr Allergy Asthma Rep        ISSN: 1529-7322            Impact factor:   4.806


  72 in total

1.  Role of local eosinophilopoietic processes in the development of airway eosinophilia in prednisone-dependent severe asthma.

Authors:  R Sehmi; S G Smith; M Kjarsgaard; K Radford; L-P Boulet; C Lemiere; C M Prazma; H Ortega; J G Martin; P Nair
Journal:  Clin Exp Allergy       Date:  2016-06       Impact factor: 5.018

Review 2.  Early-Life Origins of Chronic Obstructive Pulmonary Disease.

Authors:  Fernando D Martinez
Journal:  N Engl J Med       Date:  2016-09-01       Impact factor: 91.245

3.  A Randomized Trial of Single-Dose Oral Dexamethasone Versus Multidose Prednisolone for Acute Exacerbations of Asthma in Children Who Attend the Emergency Department.

Authors:  John J Cronin; Siobhan McCoy; Una Kennedy; Sinéad Nic An Fhailí; Abel Wakai; John Hayden; Gloria Crispino; Michael J Barrett; Sean Walsh; Ronan O'Sullivan
Journal:  Ann Emerg Med       Date:  2015-10-14       Impact factor: 5.721

4.  Tiotropium add-on therapy in adolescents with moderate asthma: A 1-year randomized controlled trial.

Authors:  Eckard Hamelmann; Eric D Bateman; Christian Vogelberg; Stanley J Szefler; Mark Vandewalker; Petra Moroni-Zentgraf; Mandy Avis; Anna Unseld; Michael Engel; Attilio L Boner
Journal:  J Allergy Clin Immunol       Date:  2016-03-05       Impact factor: 10.793

5.  Exhaled nitric oxide in children with asthma receiving Xolair (omalizumab), a monoclonal anti-immunoglobulin E antibody.

Authors:  Philip E Silkoff; Francisco A Romero; Niroo Gupta; Robert G Townley; Henry Milgrom
Journal:  Pediatrics       Date:  2004-04       Impact factor: 7.124

Review 6.  Severe Asthma in Children: Lessons Learned and Future Directions.

Authors:  Anne M Fitzpatrick
Journal:  J Allergy Clin Immunol Pract       Date:  2016 Jan-Feb

7.  Peripheral eosinophil counts as a marker of disease activity in intrinsic and extrinsic asthma.

Authors:  C S Ulrik
Journal:  Clin Exp Allergy       Date:  1995-09       Impact factor: 5.018

8.  Exhaled volatile organic compounds predict exacerbations of childhood asthma in a 1-year prospective study.

Authors:  Charlotte M Robroeks; Joep J van Berkel; Quirijn Jöbsis; Frederik-Jan van Schooten; Jan W Dallinga; Emiel F Wouters; Edward Dompeling
Journal:  Eur Respir J       Date:  2013-05-03       Impact factor: 16.671

9.  Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals.

Authors:  Go Takayama; Kazuhiko Arima; Taisuke Kanaji; Shuji Toda; Hiroyuki Tanaka; Shunsuke Shoji; Andrew N J McKenzie; Hiroichi Nagai; Takao Hotokebuchi; Kenji Izuhara
Journal:  J Allergy Clin Immunol       Date:  2006-04-27       Impact factor: 10.793

10.  Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.

Authors:  Elisabeth H Bel; Sally E Wenzel; Philip J Thompson; Charlene M Prazma; Oliver N Keene; Steven W Yancey; Hector G Ortega; Ian D Pavord
Journal:  N Engl J Med       Date:  2014-09-08       Impact factor: 91.245

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  2 in total

Review 1.  Biologics to Treat Severe Asthma in Children and Adolescents: A Practical Update.

Authors:  Gian Luigi Marseglia; Amelia Licari; Maria Angela Tosca; Giorgio Ciprandi
Journal:  Pediatr Allergy Immunol Pulmonol       Date:  2020-11-13       Impact factor: 0.885

2.  Targeted Therapy for Severe Asthma in Children and Adolescents: Current and Future Perspectives.

Authors:  Amelia Licari; Sara Manti; Riccardo Castagnoli; Giuseppe Fabio Parisi; Carmelo Salpietro; Salvatore Leonardi; Gian Luigi Marseglia
Journal:  Paediatr Drugs       Date:  2019-08       Impact factor: 3.930

  2 in total

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