Literature DB >> 2835267

Gamma-subunit of mouse retinal cyclic-GMP phosphodiesterase: cDNA and corresponding amino acid sequence.

N Tuteja1, D B Farber.   

Abstract

The cDNA nucleotide and corresponding amino acid sequences of the gamma-subunit of cyclic-GMP phosphodiesterase (cGMP-PDE gamma) from mouse retina have been determined. The cDNA translated region was found to be 91.5% homologous to the cDNA coding region for the enzyme from bovine retina [(1986) FEBS Lett. 204, 288-292]. On Northern blots of normal mouse retinal RNAs this cDNA hybridized the cGMP-PDE gamma mRNA which is 900 bp long. The mouse gamma-subunit contains 87 amino acid residues which share 97.7% homology with the bovine polypeptide [(1986) FEBS Lett. 204, 288-292]. Only two amino acids have been changed, Ala 8 to Gly and Met 17 to Ile.

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Year:  1988        PMID： 2835267     DOI： 10.1016/0014-5793(88)80413-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

1.  Removal of phosphorylation sites of gamma subunit of phosphodiesterase 6 alters rod light response.

Authors:  S H Tsang; M L Woodruff; Kerstin M Janisch; M C Cilluffo; D B Farber; G L Fain
Journal:  J Physiol       Date:  2006-11-30       Impact factor: 5.182

2.  Genomic organization and complete sequence of the human gene encoding the beta-subunit of the cGMP phosphodiesterase and its localisation to 4p 16.3.

Authors:  B Weber; O Riess; G Hutchinson; C Collins; B Y Lin; D Kowbel; S Andrew; K Schappert; M R Hayden
Journal:  Nucleic Acids Res       Date:  1991-11-25       Impact factor: 16.971

3.  Function of the asparagine 74 residue of the inhibitory γ-subunit of retinal rod cGMP-phophodiesterase (PDE) in vivo.

Authors:  Stephen H Tsang; Michael L Woodruff; Chun Wei Hsu; Matthew C Naumann; Marianne Cilluffo; Joaquin Tosi; Chyuan-Sheng Lin
Journal:  Cell Signal       Date:  2011-05-15       Impact factor: 4.315

4.  Effect of the ILE86TER mutation in the γ subunit of cGMP phosphodiesterase (PDE6) on rod photoreceptor signaling.

Authors:  Stephen H Tsang; Michael L Woodruff; Chyuan-Sheng Lin; Barry D Jacobson; Matthew C Naumann; Chun Wei Hsu; Richard J Davis; Marianne C Cilluffo; Jeannie Chen; Gordon L Fain
Journal:  Cell Signal       Date:  2011-09-08       Impact factor: 4.315

5.  Localization of three genes expressed in retina on mouse chromosome 11.

Authors:  C A Kozak; M Danciger; C Bowes; M C Adamson; K Palczewski; A S Polans; D B Farber
Journal:  Mamm Genome       Date:  1995-02       Impact factor: 2.957

6.  In vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84.

Authors:  S H Tsang; C K Yamashita; K Doi; D J Salchow; N Bouvier; M Mendelsohn; P Gouras; D B Farber; S P Goff
Journal:  Biochem J       Date:  2001-02-01       Impact factor: 3.857

7.  Phosphatidylinositol-stimulated phosphorylation of an inhibitory subunit of cGMP phosphodiesterase in vertebrate rod photoreceptors.

Authors:  F Hayashi; G Y Lin; H Matsumoto; A Yamazaki
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

8.  Domain mapping of the retinal cyclic GMP phosphodiesterase gamma-subunit. Function of the domains encoded by the three exons of the gamma-subunit gene.

Authors:  D J Takemoto; D Hurt; B Oppert; J Cunnick
Journal:  Biochem J       Date:  1992-02-01       Impact factor: 3.857

9.  Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase.

Authors:  S H Tsang; P Gouras; C K Yamashita; H Kjeldbye; J Fisher; D B Farber; S P Goff
Journal:  Science       Date:  1996-05-17       Impact factor: 47.728

10.  Identification of molecular markers of bipolar cells in the murine retina.

Authors:  Douglas S Kim; Sarah E Ross; Jeffrey M Trimarchi; John Aach; Michael E Greenberg; Constance L Cepko
Journal:  J Comp Neurol       Date:  2008-04-10       Impact factor: 3.215
  10 in total

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