| Literature DB >> 28351428 |
Yi Fang Lee1, Lance David Miller2, Xiu Bin Chan1, Michael A Black3, Brendan Pang4, Chee Wee Ong4, Manuel Salto-Tellez5,6, Edison T Liu7, Kartiki V Desai8.
Abstract
Entities:
Year: 2017 PMID: 28351428 PMCID: PMC5369187 DOI: 10.1186/s13058-017-0830-9
Source DB: PubMed Journal: Breast Cancer Res ISSN: 1465-5411 Impact factor: 6.466
Fig. 8JMJD6 expression affects SMAD phosphorylation. Immunoblots show that the level of total SMAD2/3, phosphorylated SMAD2 and phosphorylated SMAD3 are decreased in MCF-7 J1-OE clones, and increased in JMJD6 siRNA-mediated knock-down in MCF-7 and MDA-MB231. The numbers next to the SMAD2P/3P denote the expected sites of phosphorylation detected by the antibodies. N.S. denotes non-specific bands from the blots which indicate equal loading of the protein lysates