Literature DB >> 28349412

Evaluating Outcomes for Older Patients with Parkinson's Disease or Dementia with Lewy Bodies who have been Hospitalised for Hip Fracture Surgery: Potential Impact of Drug Administration.

Marie Enemark1,2, Mette Midttun3, Kristian Winge4.   

Abstract

INTRODUCTION: People with Parkinson's disease (PD) are at risk of falling and have an increased risk of complications and prolonged recovery during hospitalisation.
OBJECTIVE: The aim of this study was to investigate the rate of complications and recovery related to a hip fracture in patients with PD.
METHODS: All patients with PD or dementia with Lewy bodies (DLB) and a hip fracture who were admitted from January 2013 through June 2014 (18 months) to the Department of Orthopaedics, Copenhagen University Hospital, Herlev, Denmark were evaluated. Data regarding duration of admission, complications, timing of administration of anti-PD medication, and level of mobility at discharge were obtained from files of patients with PD or DLB and compared with data from a comparable group of patients who were admitted with a hip fracture and chronic obstructive pulmonary disease (COPD).
RESULTS: A total of 31 patients with PD or DLB (PD/DLB group) and 45 patients with COPD (COPD group) were registered during the timeframe investigated. The patients in the PD/DLB group were significantly (p < 0.05) younger than those in the COPD group (77.7 vs. 80.7 years, respectively) and had lower co-morbidity scores (0.9 vs 2.6, respectively). There were no significant differences in length of stay, delirium, or number of infections between the groups. Two thirds of patients with PD were not able to walk unassisted at discharge. Less than 50% of anti-PD medication was given within ±1 h of the scheduled time.
CONCLUSIONS: Although patients with PD/DLB are significantly younger and have significantly lower degrees of co-morbidity than patients with COPD, their course and recovery after surgery are equivalent to those of patients with COPD. Patients with PD/DLB are at high risk of developing complications during hospital admission for hip fracture.

Entities:  

Mesh:

Year:  2017        PMID: 28349412     DOI: 10.1007/s40266-017-0454-x

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  22 in total

1.  Continuous subcutaneous apomorphine as replacement for levodopa in severe parkinsonian patients after surgery.

Authors:  E Broussolle; M H Marion; P Pollak
Journal:  Lancet       Date:  1992-10-03       Impact factor: 79.321

2.  Managing Parkinson's disease during surgery.

Authors:  K A Brennan; R W Genever
Journal:  BMJ       Date:  2010-11-01

3.  Is there an increased risk of hip fracture in Parkinson's disease? A nationwide inpatient sample.

Authors:  Rajib K Bhattacharya; Richard M Dubinsky; Sue Min Lai; Hilary Dubinsky
Journal:  Mov Disord       Date:  2012-06-28       Impact factor: 10.338

4.  Hip fractures in people with idiopathic Parkinson's disease: incidence and outcomes.

Authors:  Richard W Walker; Andrew Chaplin; Rebecca L Hancock; Rachel Rutherford; William K Gray
Journal:  Mov Disord       Date:  2013-02-06       Impact factor: 10.338

5.  Relative mortality in U.S. Medicare beneficiaries with Parkinson disease and hip and pelvic fractures.

Authors:  Marcie Harris-Hayes; Allison W Willis; Sandra E Klein; Sylvia Czuppon; Beth Crowner; Brad A Racette
Journal:  J Bone Joint Surg Am       Date:  2014-02-19       Impact factor: 5.284

6.  Impact of Parkinson's disease on the acute care treatment and medium-term functional outcome in geriatric hip fracture patients.

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7.  [Perioperative management of a patient with Parkinson's disease with intravenous infusion of levodopa].

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Review 8.  Parkinson's disease patients who fracture their neck of femur: a review of outcome data.

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Review 9.  The prevalence of Parkinson's disease: a systematic review and meta-analysis.

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Journal:  Mov Disord       Date:  2014-06-28       Impact factor: 10.338

10.  Does a specialist unit improve outcomes for hospitalized patients with Parkinson's disease?

Authors:  Rob Skelly; Lisa Brown; Apostolos Fakis; Lindsey Kimber; Charlotte Downes; Fiona Lindop; Clare Johnson; Caroline Bartliff; Nin Bajaj
Journal:  Parkinsonism Relat Disord       Date:  2014-09-18       Impact factor: 4.891

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3.  The Neuromodulatory Impact of Subthalamic Nucleus Deep Brain Stimulation on Gait and Postural Instability in Parkinson's Disease Patients: A Prospective Case Controlled Study.

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4.  Letter to the Editor Regarding "Hip Fracture Care in Parkinson Disease: A Retrospective Analysis of 1,239 Patients".

Authors:  Xinxing Fei; Yue Hu
Journal:  Geriatr Orthop Surg Rehabil       Date:  2022-10-06
  4 in total

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