Literature DB >> 28348473

Acute Onset Significant Muscle Weakness in a Patient Awaiting Liver Transplantation: Look for Statins.

Narendra S Choudhary1, Sanjiv Saigal1, Neeraj Saraf1, Arvinder S Soin1.   

Abstract

Statins are commonly used drugs in patients with liver and cardiac disease. Statin-induced severe myopathy is a very uncommon presentation and rhabdomyolysis may occur in extreme cases which leads to renal failure. Patients with comorbidities like diabetes, hypothyroidism, and liver disease have higher chances of development of statin-induced myopathy. We describe a case of Child's C cirrhosis wherein the patient had acute onset significant muscle weakness and improved on statin discontinuation.

Entities:  

Keywords:  CK, creatine kinase; EMG, electromyography; TSH, thyroid function test; cirrhosis; muscle; myopathy; statin

Year:  2016        PMID: 28348473      PMCID: PMC5357716          DOI: 10.1016/j.jceh.2016.09.007

Source DB:  PubMed          Journal:  J Clin Exp Hepatol        ISSN: 0973-6883


  12 in total

1.  ACC/AHA/NHLBI clinical advisory on the use and safety of statins.

Authors:  Richard C Pasternak; Sidney C Smith; C Noel Bairey-Merz; Scott M Grundy; James I Cleeman; Claude Lenfant
Journal:  J Am Coll Cardiol       Date:  2002-08-07       Impact factor: 24.094

2.  Statins Reduce the Risk of Cirrhosis and Its Decompensation in Chronic Hepatitis B Patients: A Nationwide Cohort Study.

Authors:  Yi-Wen Huang; Chia-Long Lee; Sien-Sing Yang; Szu-Chieh Fu; Yun-Yi Chen; Ting-Chuan Wang; Jui-Ting Hu; Ding-Shinn Chen
Journal:  Am J Gastroenterol       Date:  2016-05-10       Impact factor: 10.864

Review 3.  Statin-associated myopathy: from genetic predisposition to clinical management.

Authors:  M Vrablik; L Zlatohlavek; T Stulc; V Adamkova; M Prusikova; L Schwarzova; J A Hubacek; R Ceska
Journal:  Physiol Res       Date:  2014       Impact factor: 1.881

Review 4.  Evidence-based management of statin myopathy.

Authors:  Charles R Harper; Terry A Jacobson
Journal:  Curr Atheroscler Rep       Date:  2010-09       Impact factor: 5.113

5.  Statins Are Associated With a Decreased Risk of Decompensation and Death in Veterans With Hepatitis C-Related Compensated Cirrhosis.

Authors:  Arpan Mohanty; Janet P Tate; Guadalupe Garcia-Tsao
Journal:  Gastroenterology       Date:  2015-10-17       Impact factor: 22.682

Review 6.  Mechanisms and assessment of statin-related muscular adverse effects.

Authors:  Dirk Moßhammer; Elke Schaeffeler; Matthias Schwab; Klaus Mörike
Journal:  Br J Clin Pharmacol       Date:  2014-09       Impact factor: 4.335

Review 7.  Statin-induced myopathy: a review and update.

Authors:  Thura T Abd; Terry A Jacobson
Journal:  Expert Opin Drug Saf       Date:  2011-02-23       Impact factor: 4.250

Review 8.  The broad spectrum of statin myopathy: from myalgia to rhabdomyolysis.

Authors:  Charles R Harper; Terry A Jacobson
Journal:  Curr Opin Lipidol       Date:  2007-08       Impact factor: 4.776

Review 9.  Narrative review: statin-related myopathy.

Authors:  Tisha R Joy; Robert A Hegele
Journal:  Ann Intern Med       Date:  2009-06-16       Impact factor: 25.391

Review 10.  Statin-induced Myopathy in Skeletal Muscle: the Role of Exercise.

Authors:  Hyo-Bum Kwak
Journal:  J Lifestyle Med       Date:  2014-09-30
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  1 in total

1.  Editorial: Statins and Liver Disease: Is it Time to Recommend Statins to Prevent Liver Disease Progression?

Authors:  Jennifer C Price; Phyllis C Tien
Journal:  Am J Gastroenterol       Date:  2017-10       Impact factor: 10.864

  1 in total

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