Simon E Kolstoe1, Daniel R Shanahan2, Janet Wisely3. 1. Institute of Biomedical and Biomolecular Science, University of Portsmouth, Portsmouth, UK. 2. Health Sciences, BioMed Central, London, UK. 3. Health Research Authority, London, UK Janet.wisely@nhs.net simon.kolstoe@port.ac.uk Janet.wisely@nhs.net.