Samantha E Montag1, Kristen L Knutson2, Phyllis C Zee2, Jeffrey J Goldberger3, Jason Ng3, Kwang-Youn A Kim1, Mercedes R Carnethon4. 1. Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL. 2. Center for Circadian and Sleep Medicine, Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL. 3. Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL. 4. Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL. Electronic address: carnethon@northwestern.edu.
Abstract
OBJECTIVES: To investigate the association of sleep characteristics with prevalent hypertension, diabetes, and obesity in a multiethnic cohort. DESIGN: This study used a population-based cross-sectional study design. SETTING: Participants were recruited between 2009 and 2011 from Chicago, Illinois, and the surrounding suburbs. PARTICIPANTS: Participants were 492 adults aged 35 to 64years who self-reported as white, black, Hispanic, or Asian and who had a low likelihood of sleep apnea based on the apnea screening questionnaires and 1 night of apnea screening using an in-home device (apnea hypopnea index <15 or oxygen desaturation index <10). MEASUREMENTS: Participants wore a wrist actigraphy monitor (Actiwatch™) for 7days. During a clinical examination, participants completed questionnaires about sleep, other health behaviors, and medical history and had their blood pressure, anthropometric measures, and fasting blood glucose measured; metabolic risk factors were determined based on standard clinical guidelines. RESULTS: The prevalence of hypertension, obesity, and diabetes was 17.1%, 5.5%, and 35.4%, respectively. Sleep duration was not associated with any cardiovascular risk factor. There was a significantly increased odds for hypertension (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01-1.08) and obesity (OR, 1.03; 95% CI, 1.00-1.05) associated with higher sleep fragmentation (per 1%). There was also a significantly increased odds for hypertension associated with poorer self-reported sleep quality (OR, 1.14 [95% CI, 1.05-1.24] per 1-unit higher Pittsburgh Sleep Quality Index global score). CONCLUSION: Objective and self-reported sleep quality may be more important than duration in relation to prevalent hypertension.
OBJECTIVES: To investigate the association of sleep characteristics with prevalent hypertension, diabetes, and obesity in a multiethnic cohort. DESIGN: This study used a population-based cross-sectional study design. SETTING:Participants were recruited between 2009 and 2011 from Chicago, Illinois, and the surrounding suburbs. PARTICIPANTS: Participants were 492 adults aged 35 to 64years who self-reported as white, black, Hispanic, or Asian and who had a low likelihood of sleep apnea based on the apnea screening questionnaires and 1 night of apnea screening using an in-home device (apnea hypopnea index <15 or oxygen desaturation index <10). MEASUREMENTS: Participants wore a wrist actigraphy monitor (Actiwatch™) for 7days. During a clinical examination, participants completed questionnaires about sleep, other health behaviors, and medical history and had their blood pressure, anthropometric measures, and fasting blood glucose measured; metabolic risk factors were determined based on standard clinical guidelines. RESULTS: The prevalence of hypertension, obesity, and diabetes was 17.1%, 5.5%, and 35.4%, respectively. Sleep duration was not associated with any cardiovascular risk factor. There was a significantly increased odds for hypertension (odds ratio [OR], 1.05; 95% confidence interval [CI], 1.01-1.08) and obesity (OR, 1.03; 95% CI, 1.00-1.05) associated with higher sleep fragmentation (per 1%). There was also a significantly increased odds for hypertension associated with poorer self-reported sleep quality (OR, 1.14 [95% CI, 1.05-1.24] per 1-unit higher Pittsburgh Sleep Quality Index global score). CONCLUSION: Objective and self-reported sleep quality may be more important than duration in relation to prevalent hypertension.
Authors: Nicole G Altman; Bilgay Izci-Balserak; Elizabeth Schopfer; Nicholas Jackson; Pinyo Rattanaumpawan; Philip R Gehrman; Nirav P Patel; Michael A Grandner Journal: Sleep Med Date: 2012-11-08 Impact factor: 3.492
Authors: Laura J Rasmussen-Torvik; Peter John D De Chavez; Kiarri N Kershaw; Samantha E Montag; Kristen L Knutson; Kwang-Youn A Kim; Phyllis C Zee; Mercedes R Carnethon Journal: Am J Hypertens Date: 2016-12-01 Impact factor: 2.689
Authors: Mercedes R Carnethon; Peter John De Chavez; Phyllis C Zee; Kwang-Youn A Kim; Kiang Liu; Jeffrey J Goldberger; Jason Ng; Kristen L Knutson Journal: Sleep Med Date: 2015-07-26 Impact factor: 3.492
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